312904-86-2 Usage
General Description
[(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester is a chemical compound with the molecular formula C10H18N2O6. It is an ester derivative of the amino acid glycine and is commonly used as a coupling agent in peptide synthesis. [(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester plays a crucial role in solid-phase peptide synthesis by facilitating the coupling of amino acids to form peptide bonds. It is also utilized as a reagent in the production of pharmaceuticals and bioactive compounds. Additionally, it is known for its ability to improve the yield and purity of peptide synthesis reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 312904-86-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,9,0 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 312904-86:
(8*3)+(7*1)+(6*2)+(5*9)+(4*0)+(3*4)+(2*8)+(1*6)=122
122 % 10 = 2
So 312904-86-2 is a valid CAS Registry Number.
312904-86-2Relevant articles and documents
Development of a scaleable synthesis of a 3-aminopyrazinone acetamide thrombin inhibitor
Ashwood, Michael S.,Alabaster, Ramon J.,Cottrell, Ian F.,Cowden, Cameron J.,Davies, Antony J.,Dolling, Ulf H.,Emerson, Khateeta M.,Gibb, Andrew D.,Hands, David,Wallace, Debra J.,Wilson, Robert D.
, p. 192 - 200 (2013/09/04)
A scaleable route to 2-{3-[(2,2-difluoro-2-(2-pyridyl)ethyl)-animo]-6- chloro-2-oxohydropyrazinyl}-N-(3-fluoro(2-pyridyl))-methyl]acetamide 1 is described in which various scaleup issues were addressed to provide a safe, efficient, and robust route for th
Process for making a thrombin inhibitor
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, (2008/06/13)
The invention is a process for preparing 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide which comprises coupling with 2-aminomethyl-3-fluoropyridine dihydrochloric acid salt in the presence of a coupling reagent and a base to form 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide.
