31350-27-3 Usage
Description
NSC 351869, also known as 1,4-Di-2-furoyl-piperazine (Terazosin EP Impurity M), is a chemical compound that is used as an impurity in Terazosin, a medication used to treat high blood pressure and benign prostatic hyperplasia. It is a derivative of piperazine, a heterocyclic amine, and contains two furoyl groups attached to the piperazine ring.
Uses
Used in Pharmaceutical Industry:
NSC 351869 is used as an impurity in Terazosin for the treatment of high blood pressure and benign prostatic hyperplasia. It helps in maintaining the quality and purity of the drug.
Used in Biological Studies:
NSC 351869 is used in biological studies to examine the relationship of structure to parasiticide activity of nitrated derivatives. This helps in understanding the structure-activity relationship and the potential use of nitrated derivatives as parasiticides.
Check Digit Verification of cas no
The CAS Registry Mumber 31350-27-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,3,5 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 31350-27:
(7*3)+(6*1)+(5*3)+(4*5)+(3*0)+(2*2)+(1*7)=73
73 % 10 = 3
So 31350-27-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N2O4/c17-13(11-3-1-9-19-11)15-5-7-16(8-6-15)14(18)12-4-2-10-20-12/h1-4,9-10H,5-8H2
31350-27-3Relevant articles and documents
HMDS-promoted in situ amidation reactions of carboxylic acids and amines
Chou, Wen-Chih,Chou, Ming-Chen,Lu, Yann-Yu,Chen, Shyh-Fong
, p. 3419 - 3422 (1999)
A number of N-acylalkylenediamines were synthesized in high yields by in situ monoamidation of carboxylic acids with diamines. The amidation reactions were carried out simply by heating the substrates at 110 °C for 5-24 h in the presence of HMDS.