313657-75-9

Basic information

• Product Name: (R)-4-N-TRITYL-2-METHYL PIPERAZINE
• Synonyms: (R)-3-METHYL-1-TRITYL-PIPERAZINE;(R)-4-N-TRITYL-2-METHYL PIPERAZINE;1-TRITYL-(R)-3-METHYLPIPERAZINE;(R)-2-Methyl-4-(triphenylmethyl)piperazine~(R)-2-Methyl-4-tritylpiperazine;(R)-2-Methyl-4-tritylpiperazine;1-TRITYL-(R)-3-METHYLPIPERAZINE, 98%, EE 99%;R-4-TRITYL-2-METHYL PIPERAZINE;(R)-2-Methyl-4-(triphenylmethyl)piperazine
• CAS NO: 313657-75-9
• Molecular Formula: C₂₄H₂₆N₂
• Molecular Weight: 342.48
• EINECS: -0
• Mol File: 313657-75-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 128°C
• Boiling Point: 451.7°C at 760 mmHg
• Flash Point: 145.3°C
• Appearance: /
• Density: 1.074g/cm³
• Vapor Pressure: 2.39E-08mmHg at 25°C
• Refractive Index: 1.589
• PKA: 9.04±0.40(Predicted)
• CAS DataBase Reference: (R)-4-N-TRITYL-2-METHYL PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-N-TRITYL-2-METHYL PIPERAZINE(313657-75-9)
• EPA Substance Registry System: (R)-4-N-TRITYL-2-METHYL PIPERAZINE(313657-75-9)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36
• Hazardous Substances Data: 313657-75-9(Hazardous Substances Data)

Usage

General Description

(R)-4-N-TRITYL-2-METHYL PIPERAZINE is a chemical compound with the molecular formula C31H33N3. It is a piperazine derivative that is commonly used in the synthesis of pharmaceutical compounds, particularly in the development of new drugs. (R)-4-N-TRITYL-2-METHYL PIPERAZINE is characterized by the presence of a trityl group and a methyl group attached to the piperazine ring. It is known for its potential applications in the fields of medicinal chemistry and drug discovery due to its ability to interact with biological targets and exhibit pharmacological activity. (R)-4-N-TRITYL-2-METHYL PIPERAZINE is an important intermediate in the synthesis of various biologically active compounds and is widely utilized in the pharmaceutical industry for the development of new therapeutic agents.

InChI:InChI=1/C24H26N2/c1-20-19-26(18-17-25-20)24(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,20,25H,17-19H2,1H3/t20-/m0/s1

Upstream product

• 75336-86-6 (2R)-methylpiperazine 
• 76-83-5 trityl chloride 
• 126458-16-0 (R)-2-methylpiperazine, L-tartrate 
• 109-07-9 (RS)-2-methylpiperazine 

Downstream Products

• 531503-76-1 (R)-1-(3-chloro-2-pyrazinyl)-2-methyl-4-tritylpiperazine 
• 313657-76-0 (R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine 
• 639029-52-0 (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride 

Relevant articles and documents

Synthesis of PNU-243922 labelled with 14C

The arylpiperazine PNU-243922 (1) has been labelled with 14C. A two-step sequence starting from the 14C labelled alcohol 6a led to radiochemically pure (> 98%) [14C]PNU-243922 with a specific activity of 546 MBq/mmol. Copyright

Novel compounds and their use

Compounds of the general formula (I): wherein R1, R2, R3 and R4 are as described in the specification. Further included are pharmaceutical compositions comprising the compounds, processes for their preparation,