31450-61-0Relevant articles and documents
Asymmetric olefin isomerization of butenolides via proton transfer catalysis by an organic molecule
Wu, Yongwei,Singh, Ravi P.,Deng, Li
supporting information; scheme or table, p. 12458 - 12461 (2011/10/09)
An unprecedented enantioselective and general olefin isomerization was realized via biomimetic proton transfer catalysis with a new chiral organic catalyst. A broad range of mono- and disubstituted β,γ-unsaturated butenolides were transformed into the corresponding chiral α,β- unsaturated butenolides in high enantioselectivity and yield in the presence of as low as 0.5 mol % catalyst. Mechanistic studies have revealed the protonation as the rate-determining step.
