31518-13-5

Basic information

• Product Name: 5,6-DIHYDRO-4H-PYRAN-2-CARBONITRILE
• Synonyms: 5,6-DIHYDRO-4H-PYRAN-2-CARBONITRILE;5,6-Dihydro-4H-pyran-2-carbonitrile 2-Cyano-4,5-dihydropyran;2-Cyano-5,6-dihydro-4H-pyran;3,4-dihydro-2H-pyran-6-carbonitrile
• CAS NO: 31518-13-5
• Molecular Formula: C6H7NO
• Molecular Weight: 109.13
• Product Categories: Boron, Nitrile, Thio,& TM-Cpds;Heterocycles;pharmacetical
• Mol File: 31518-13-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 195.2 °C at 760 mmHg
• Flash Point: 78.5 °C
• Appearance: /
• Density: 1.06 g/cm³
• Vapor Pressure: 0.425mmHg at 25°C
• Refractive Index: 1.481
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5,6-DIHYDRO-4H-PYRAN-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DIHYDRO-4H-PYRAN-2-CARBONITRILE(31518-13-5)
• EPA Substance Registry System: 5,6-DIHYDRO-4H-PYRAN-2-CARBONITRILE(31518-13-5)

Safety Data

• Hazardous Substances Data: 31518-13-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthesis, p. 548, 1986 DOI: 10.1055/s-1986-31697

InChI:InChI=1/C6H7NO/c7-5-6-3-1-2-4-8-6/h3H,1-2,4H2

Upstream product

• 1051940-71-6 3-Bromo-tetrahydro-pyran-2-carbonitrile 
• 110-87-2 3,4-dihydro-2H-pyran 
• 544-92-3 copper(I) cyanide 
• 56660-59-4 2,3-dibromotetrahydropyran 

Downstream Products

• 31518-14-6 3,4-dihydro-2H-pyran-6-carboxylic acid 
• 129201-92-9 5,6-dihydro-4H-pyran-2-carboxylic acid methyl ester 
• 105499-32-9 (S)-(-)-Tetrahydropyran-2-carboxylic Acid 

Relevant articles and documents

Iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids

Spiral binding: A highly enantioselective hydrogenation of unsaturated heterocyclic acids has been developed by using chiral iridium/spirophosphino oxazoline catalysts (see scheme; BArF-=tetrakis[3,5- bis(trifluoromethyl)phenyl]borate, Boc=tert-butoxycarbonyl). This reaction provided an efficient method for the preparation of optically active heterocyclic acids with excellent enantioselectivities. Copyright

One-Pot Preparation of α-Cyanovinyl Ethers (2-Alkoxy-2-alkenenitriles) from Vinyl Ethers: Elaboration to 3-Alkoxy-2-oxo-3-alkenenitriles and Aluminium Chloride-Catalyzed Cycloadditions to Cyclopentadiene

A variety of α-cyanovinyl ethers have been prepared by 3 different routes and elaborated to 3-alkoxy-2-oxo-3-alkenenitriles.The latter, in the presence of cyclopentadiene and aluminium chloride, give novel bridged 7-membered cycloadducts with loss of hydrogen cyanide.