3152-12-3 Usage
Description
2,2'-DICHLOROBENZILIC ACID, also known as 2,2'-Bis(2-chlorophenyl)-2-hydroxyacetic Acid, is an organic compound that serves as a valuable intermediate in the synthesis of various chemical compounds. It is characterized by its unique molecular structure, which includes a central hydroxyacetic acid group connected to two chlorophenyl rings. This structure endows it with specific chemical properties that make it useful in a range of applications.
Uses
Used in Pharmaceutical Industry:
2,2'-DICHLOROBENZILIC ACID is used as an intermediate in the synthesis of substituted benzilic acid derivatives for their antimicrobial properties. These derivatives have potential applications in the development of new drugs and therapies to combat various microbial infections, including bacterial and fungal diseases.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2,2'-DICHLOROBENZILIC ACID is utilized as a key building block for creating a variety of complex organic molecules. Its unique structure allows for further functionalization and modification, making it a versatile component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research and Development:
2,2'-DICHLOROBENZILIC ACID is also employed in research and development settings, where it is used to study the structure-activity relationships of various chemical compounds. This knowledge can be applied to design and develop new molecules with improved properties and applications in various industries, such as pharmaceuticals, materials science, and environmental science.
Check Digit Verification of cas no
The CAS Registry Mumber 3152-12-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,5 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3152-12:
(6*3)+(5*1)+(4*5)+(3*2)+(2*1)+(1*2)=53
53 % 10 = 3
So 3152-12-3 is a valid CAS Registry Number.
3152-12-3Relevant articles and documents
PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZILIC ACID FROM SUBSTITUTED BENZILS
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Page/Page column 3, (2010/10/19)
The classical process for the rearrangement of substituted benzil to benzilic acid is performed in the presence of sodium or potassium hydroxide as a base using ethanol-ether as a medium. The reaction requires reflux temperature for complete conversion. However, these bases containing metallic ions and generate metallic containing effluent waste which may require additional expenditure for treatment. Moreover, because of corrosive nature of base, and use of flammable solvent, the safety measures are needed during large scale production. Another method also reported for benzilic acid rearrangement at 380° C. which is practically not feasible. The present invention describes the use of quaternary ammonium hydroxides as a base for the rearrangement of the substituted benzils to benzilc acids. It also avoids the use of solvent and reaction can be carried out at relatively lower temperatures. Because of the solvent free reaction condition it reduces the mass/volume of reaction mixture.
