3156-37-4

Basic information

• Product Name: Benzene,1-bromo-4-(2-nitroethenyl)-
• Synonyms: Styrene,p-bromo-b-nitro- (7CI,8CI); 1-Bromo-4-(2-nitroethenyl)benzene; 1-Bromo-4-(2-nitrovinyl)benzene; 4-Bromo-b-nitrostyrene; NSC 121158; p-Bromo-b-nitrostyrene; p-Bromo-w-nitrostyrene
• CAS NO: 3156-37-4
• Molecular Formula: C₈H₆BrNO₂
• Molecular Weight: 228.0427
• Mol File: 3156-37-4.mol
• Article Data: 110

Chemical Properties

• Boiling Point: 318.9°Cat760mmHg
• Flash Point: 146.7°C
• Density: 1.596g/cm³
• CAS DataBase Reference: Benzene,1-bromo-4-(2-nitroethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1-bromo-4-(2-nitroethenyl)-(3156-37-4)
• EPA Substance Registry System: Benzene,1-bromo-4-(2-nitroethenyl)-(3156-37-4)

Safety Data

• Hazardous Substances Data: 3156-37-4(Hazardous Substances Data)

Upstream product

• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 75-52-5 nitromethane 
• 1122-91-4 4-bromo-benzaldehyde 
• 135711-38-5 [1-(4-Bromo-phenyl)-2-nitro-ethyl]-butyl-amine 
• 1200-07-3 3-(4-bromophenyl)acrylic acid 
• 17104-98-2 1-(4-bromophenyl)-2-nitroethanol 
• 2826-24-6 4-bromobenzylidenemalononitrile 
• 1402933-44-1 C₁₁H₈BrN₃O₂ 
• 1200-07-3 trans-4-bromocinnamic acid 

Downstream Products

• 1001058-65-6 (S)-3-(4-bromophenyl)-4-nitrobutanal 
• 1369200-70-3 (2R,3S)-3-(4-bromophenyl)-2-methyl-4-nitrobutanal 
• 16298-19-4 4-{6-[1-(4-bromo-phenyl)-2-nitro-ethyl]-cyclohex-1-enyl}-morpholine 
• 92774-83-9 2-[1-(4-Bromo-phenyl)-2-nitro-ethyl]-3-hydroxy-cyclopent-2-enone 
• 344874-44-8 3-(4-Bromo-phenyl)-5,6,7,8-tetrahydro-3H-cyclohepta[b]furan-2,4-dione 2-oxime 
• 132336-05-1 [2-(4-Bromo-phenyl)-ethyl]-ethyl-amine 
• 143955-93-5 (2R,5S,1'S)-2,5-dihydro-5-isopropyl-3,6-dimethoxy-2-<2'-nitro-1'-(p-bromophenyl)-ethyl-1'>-pyrazine 
• 143868-30-8 (2R,5S,1'R)-2,5-dihydro-5-isopropyl-3,6-dimethoxy-2-<2'-nitro-1'-(p-bromophenyl)-ethyl-1'>-pyrazine 
• 344763-84-4 3-(4-Bromo-phenyl)-3,5,6,7-tetrahydro-benzofuran-2,4-dione 2-oxime 
• 82947-12-4 3-(1-(4-bromophenyl)-2-nitroethyl)pentane-2,4-dione 
• 71483-71-1 1-Bromo-4-(1,2-dibromo-2-nitro-ethyl)-benzene 
• 586-76-5 4-Bromobenzoic acid 

Relevant articles and documents

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Catalytic Asymmetric Construction of Tertiary Carbon Centers Featuring an α-Difluoromethyl Group with CF2H-CH2-NH2as the "building Block"

We report here for the first time a novel difluoromethylated ketimine building block condensed by thioisatin and difluoroethylamine, offering efficient access to a broad range of enantioenriched products bearing difluoroethylamine units (27 examples, ≤98% yield, >99% ee) in the presence of quinine-derived squaramide. Further transformation of the intermediate would generate a variety of versatile functional blocks like α-difluoromethyl amines, β-amino acid, and β-diamine with retention of the enantiomeric excess at the difluoromethyl-bound carbon.

Active Base Hybrid Organosilica Materials based on Pyrrolidine Builder Units for Fine Chemicals Production

The catalytic activity of “pyrrolidine type” fragments included or anchored in the mesoporous silica supports or polymeric frameworks have been fully reported for enantioselective transformation. Nevertheless, low attention was focused on their catalytic abilities to perform base-catalyzed reaction. Accordingly, hybrid materials including pyrrolidine fragments in the mesoporous silica supports were prepared following different synthesis methods, such as micellar and fluoride sol-gel routes in absence of structural directing agents. Their great catalytic performance was explored for various base-catalyzed reactions to the formation of C?C bond through Knoevenagel, Claisen-Schmidt and Henry condensations under microwave irradiation. The benefits of microwave irradiation combined with suitable catalytic properties of pyrrolidine hybrid materials with strong base sites and high accessibility to active centers, allowed carrying out successfully base-catalyzed condensation reactions for the production of fine chemicals. Moreover, the hybrid catalyst exhibited high selectivity and good stability over different catalytic cycles contributing to environmental sustainability.