31560-21-1

Basic information

• Product Name: (2S,4R)-Methyl 1-benzoyl-4-(tosylo×y)pyrrolidine-2-carbo×ylate
• Synonyms: (2S,4R)-Methyl 1-benzoyl-4-(tosylo×y)pyrrolidine-2-carbo×ylate;(2S,4R)-Methyl 1-benzoyl-4-(tosyloxy)pyrrolidine-2-carboxylate
• CAS NO: 31560-21-1
• Molecular Formula: C₂₀H₂₁NO₆S
• Molecular Weight: 403.44884
• Mol File: 31560-21-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2S,4R)-Methyl 1-benzoyl-4-(tosylo×y)pyrrolidine-2-carbo×ylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-Methyl 1-benzoyl-4-(tosylo×y)pyrrolidine-2-carbo×ylate(31560-21-1)
• EPA Substance Registry System: (2S,4R)-Methyl 1-benzoyl-4-(tosylo×y)pyrrolidine-2-carbo×ylate(31560-21-1)

Safety Data

• Hazardous Substances Data: 31560-21-1(Hazardous Substances Data)

Usage

General Description

"(2S,4R)-Methyl 1-benzoyl-4-(tosyloxy)pyrrolidine-2-carboxylate" is a complex organic chemical compound featuring multiple functional groups. Methyl groups denote the presence of a single carbon atom bonded with three hydrogen atoms, signifying its organic nature. 1-Benzoyl indicates the benzene ring in the compound, while the 4-tosyloxy group refers to the toluenesulfonyloxy functional group. Pyrrolidines are part of the heterocyclic organic compounds class, containing a nitrogen atom within the ring, and the 2-carboxylate group indicates a carboxylic acid ester group incorporated into the molecule. (2S,4R)-Methyl 1-benzoyl-4-(tosylo×y)pyrrolidine-2-carbo×ylate's specific steric configuration is indicated by the (2S,4R) label, representing its stereochemistry. Together, these different components comprise the complex multi-functional, multi-group compound termed "(2S,4R)-Methyl 1-benzoyl-4-(tosyloxy)pyrrolidine-2-carboxylate." Its properties, functions, and applications can widely vary depending on its environment and reactions.

Upstream product

• 31560-20-0 (2S,4R)-1-benzoyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 51-35-4 4R-4-hydroxyproline 

Downstream Products

• 652970-36-0 methyl (2S,4S)-1-benzoyl-4-phenylselenopyrrolidine-2-carboxylate 
• 56439-58-8 N,O-Dibenzoyl-L-prolinol 
• 5493-38-9 N-benzoyl-L-proline methyl ester 
• 648934-62-7 methyl (2S)-1-benzoylpyrrolidin-3-ene-2-carboxylate 
• 652970-43-9 (2S)-(1-benzoyl-3-pyrrolin-2-yl)methyl benzoate 
• 652970-37-1 methyl (1R,2S,3S,6R,7S)-4-benzoyl-4-azatricyclo[5.2.1.0^2,6]dec-8-ene-3-carboxylate 
• 652970-42-8 (2S,4S)-(1-benzoyl-4-phenylselenopyrrolidin-2-yl)methyl benzoate 

Relevant articles and documents

Synthetic study of optically active 3-azabicyclo[3.3.0]octane-2,6,8- tricarboxylic acid

Synthesis of (1R,2S,5S,6R,8S)-3-azabicyclo[3.3.0]octane-2,6,8-tricarboxylic acid (2) from trans-4-hydroxy-L-proline (5) was attempted. A Diels-Alder reaction of 3,4-dehydroproline derivative 9 and cyclopentadiene afforded a single stereoisomer 11. The Diels-Alder adduct was smoothly converted to the hydrochloride of 2 (24) via RuO4 oxidation. Although some racemization of the material or product was observed during the synthetic processes, the amino acid 24 proved to be optically pure.