3169-69-5

Basic information

• Product Name: Benzene, 1-[(4-methoxyphenyl)thio]-2-nitro-
• CAS NO: 3169-69-5
• Molecular Formula: C13H11NO3S
• Molecular Weight: 261.301
• Mol File: 3169-69-5.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(4-methoxyphenyl)thio]-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(4-methoxyphenyl)thio]-2-nitro-(3169-69-5)
• EPA Substance Registry System: Benzene, 1-[(4-methoxyphenyl)thio]-2-nitro-(3169-69-5)

Safety Data

• Hazardous Substances Data: 3169-69-5(Hazardous Substances Data)

Upstream product

• 15666-75-8 2-nitro-benzenesulfenic acid methyl ester 
• 100-66-3 methoxybenzene 
• 20912-10-1 2-nitro-benzenesulfenic acid phenyl ester 
• 696-63-9 4-Methoxybenzenethiol 
• 88-73-3 2-Chloronitrobenzene 
• 29572-51-8 2-nitrobenzenesulfenyl thiocyanate 
• 70744-47-7 (p-methoxyphenyl)tri-n-butylstannane 
• 7669-54-7 2-nitrobenzenesulfenyl chloride 
• 577-19-5 2-nitrophenyl bromide 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 3034-19-3 (2-nitrophenyl)hydrazine 
• 609-73-4 o-nitroiodobenzene 
• 552-16-9 ortho-nitrobenzoic acid 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 1771-19-3 3-methoxy-10H-phenothiazine 
• 872513-62-7 2,4-bis(1,1-dimethylethyl)-6-[[[2-[(4-methoxyphenyl)thio]phenyl]imino]methyl]phenol 
• 51517-15-8 4'-Methoxyphenyl-2-nitrosophenylsulfon 
• 61174-32-1 2-Aminophenyl-4-anisylsulfon 
• 61378-48-1 2-Azidophenyl-4-anisylsulfon 
• 3169-87-7 2-[(4-methoxyphenyl)thio]benzenamine 
• 61174-15-0 1-((4-methoxyphenyl)sulfonyl)-2-nitrobenzene 

Relevant articles and documents

Method for synthesizing asymmetric sulfide from molecular oxygen oxidation water phase under catalysis of water-soluble transition metal compound

Aiming at problems that in the prior art organic solvent pollution can be caused and a great number of reaction byproducts are generated when asymmetric sulfides are prepared, the invention disclosesa method for synthesizing an asymmetric sulfide from a molecular oxygen oxidation water phase under catalysis of a water-soluble transition metal compound. The method comprises the following steps: dispersing a sulfydryl compound and a hydrazine compound as substrates in a mole ratio of 1:1 into an alkali solution, and at 40-100 DEG C, in the presence of oxygen, and with a water-soluble transitionmetal compound as a catalyst, stirring to carry out reactions, thereby obtaining the asymmetric sulfide. By adopting the method, molecular oxygen is adopted as an oxidant, and water is adopted as a solvent, so that an organic solvent is avoided, a high yield can be achieved, and the problem of byproducts can be generally avoided.

Aerobic copper-catalyzed decarboxylative thiolation

Copper-catalyzed decarboxylative thiolation using molecular oxygen as the sole oxidant was developed. A variety of aromatic carboxylic acids including 2-nitrobenzoic acids, pentafluorobenzoic acid and several heteroaromatic carboxylic acids undergo efficient thiolation to furnish the aryl sulfides in moderate to excellent yields.

Iridium and phosphine promoted C-F bond activation: The C-S cross-coupling of aryl fluorides with diaryl disulfides to synthesize thioethers

Carbon-fluorine bond is the strongest known single bond to carbon and proved very difficult to cleave. An iridium and phosphine promoted C-F bond activation was developed, for the first time achieving the C-S cross-coupling reaction of disulfides with aryl fluorides using iridium complex. The corresponding monoarylthiolation products were obtained at moderate to good yields. Thus, it represents a new method for the synthesis of aryl sulfides through C-F bond activation.