317842-50-5

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-(2-oxoethyl)-N-2-propynyl-
• CAS NO: 317842-50-5
• Molecular Formula: C12H13NO3S
• Molecular Weight: 251.306
• Mol File: 317842-50-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-(2-oxoethyl)-N-2-propynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-(2-oxoethyl)-N-2-propynyl-(317842-50-5)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-(2-oxoethyl)-N-2-propynyl-(317842-50-5)

Safety Data

• Hazardous Substances Data: 317842-50-5(Hazardous Substances Data)

Upstream product

• 2645-02-5 methyl tosylglycinate 
• 58754-95-3 N-(2,2-dimethoxyethyl)-p-toluenesulfonamide 
• 106-96-7 propargyl bromide 
• 317842-46-9 N-(2-hydroxyethyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 133886-40-5 N-tosyl-N-allylpropargylamine 
• 317842-43-6 N-(2,2-dimethoxyethyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 

Downstream Products

• 384836-85-5 ethyl (E)-4-(N-(prop-2-ynyl)-4-methylphenylsulfonamido)but-2-enoate 
• 1446089-44-6 3-(trichloromethylcarbonylamino)-1,2,3,6-tetrahydro-1-(p-toluenesulfonyl)-5-ethyl-1-enepyridine 
• 1446089-48-0 diethyl 4-(trichloromethylcarbonylamino)-1,2,3,4-tetrahydro-2-(p-toluenesulfonyl)isoquinoline-5,6-dicarboxylate 
• 1446089-53-7 4-(trichloromethylcarbonylamino)-1,2,3,4-tetrahydro-2-(p-toluenesulfonyl)benzo[f]isoquinoline-5,8-dione 

Relevant articles and documents

Iron(III)-Catalyzed Cycloisomerizations of Acetal-Vinylidenecyclopropanes: An Efficient Synthetic Route to 1,2-Disubstituted Cyclobutenes

A novel iron(III)-catalyzed intramolecular cycloisomerization of acetal-vinylidenecyclopropanes to afford a series of halogenated 1,2-disubstituted cyclobutenes tethered with a tetrahydropyrrole has been developed. The reaction is thought to proceed through a formal iron-catalyzed Prins cyclization followed by a ring-enlarging rearrangement of the methylenecyclopropane carbocation. The present protocol provides an alternative route to functionalized disubstituted cyclobutenes and the corresponding products could be successfully transformed into eight-membered oxacyclic products.

Thiocyanate radical mediated dehydration of aldoximes with visible light and air

We developed a new means of activating aldoximes by an in situ generated thiocyanate radical from ammonium thiocyanate and molecular oxygen at room temperature. With a catalytic amount of organic dye aizenuranine as the photocatalyst, the dehydration of aldoximes proceeds smoothly under visible light irradiation, providing a simple to handle, excellent functional group tolerance, and metal-free protocol for a wide range of nitriles.

Vinyl dihydropyrans and dihydrooxazines: Cyclizations of catalytic ruthenium carbenes derived from alkynals and alkynones

A novel synthesis of 2-vinyldihydropyrans and dihydro-1,4-oxazines (morpholine derivatives) from alkynals and alkynones has been developed. The cyclizations require a mild generation of catalytic ruthenium carbenes from terminal alkynes and (trimethylsilyl)diazomethane followed by trapping with carbonyl nucleophiles. Mechanistic aspects of the new cyclizations are discussed. Setting a trap: A novel synthesis of 2-vinyldihydropyrans and dihydro-1,4-oxazines (morpholine derivatives) from alkynals and alkynones has been developed. The cyclizations require a mild generation of catalytic ruthenium carbenes from terminal alkynes and (trimethylsilyl)diazomethane followed by trapping with carbonyl nucleophiles.