318471-58-8

Basic information

• Product Name: diethyl 2-(2-fluoro-4-nitro-phenyl)propanedioate
• Synonyms: Diethyl (2-fluoro-4-nitrophenyl)malonate
• CAS NO: 318471-58-8
• Molecular Formula: C₁₃H₁₄FNO₆
• Molecular Weight: 299.25
• Mol File: 318471-58-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 377.7°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.309g/cm³
• Vapor Pressure: 6.61E-06mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: diethyl 2-(2-fluoro-4-nitro-phenyl)propanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(2-fluoro-4-nitro-phenyl)propanedioate(318471-58-8)
• EPA Substance Registry System: diethyl 2-(2-fluoro-4-nitro-phenyl)propanedioate(318471-58-8)

Safety Data

• Hazardous Substances Data: 318471-58-8(Hazardous Substances Data)

Upstream product

• 369-34-6 3,4-difluoronitrobenzene 
• 996-82-7 sodium diethylmalonate 
• 105-53-3 diethyl malonate 

Downstream Products

• 1427-07-2 2-fluoro-4-nitrotoluene 
• 315228-19-4 2-(2-fluoro-4-nitrophenyl)acetic acid 
• 1160623-38-0 ethyl 2-(2-fluoro-4-nitrophenyl)acetate 
• 1426802-94-9 C₂₃H₁₇F₆NO₄S 
• 1426805-51-7 2-(4-(ethylsulfonyl)-2-fluorophenyl)acetic acid 
• 914224-31-0 2-(4-amino-2-fluorophenyl)acetic acid 
• 1426805-47-1 2-(4-((ethoxycarbonothioyl)thio)-2-fluorophenyl)acetic acid 
• 1426805-48-2 2-(2-fluoro-4-mercaptophenyl)acetic acid 
• 1426805-49-3 ethyl 2-(4-(ethylthio)-2-fluorophenyl) acetate 
• 1426805-50-6 ethyl 2-(4-(ethylsulfonyl)-2-fluorophenyl)acetate 
• 1221119-68-1 2-(2-fluoro-4-nitrophenyl)ethan-1-ol 

Relevant articles and documents

Heterocyclic compound

The present invention relates to compound (I) or a salt thereof which has a ROR γ t inhibitory action. wherein each symbol is as defined in the specification.

NOVEL COMPOUNDS

Disclosed are novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.

CYCLOPROPYL CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF

This invention relates to new oxazolidinones having a cyclopropyl moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, streptococci and enterococci, Bacteroides spp., Clostridia spp. species, as well as acid-fast organisms such as Mycobacterium tuberculosis and other mycobacterial species. The compounds are represented by structural formula I: 1its enantiomer, diastereomer, or pharmaceutically acceptable salt or ester thereof.