319-88-0 Usage
Description
1,3,5-Trichloro-2,4,6-trifluorobenzene, also known as 1,3,5-trifluorotrichlorobenzene, is an organic compound characterized by its white to off-white crystalline appearance. It is a halogenated aromatic compound with three chlorine atoms at the 1, 3, and 5 positions and three fluorine atoms at the 2, 4, and 6 positions on a benzene ring.
Uses
Used in Chemical Synthesis:
1,3,5-Trichloro-2,4,6-trifluorobenzene is used as a reagent in various chemical synthesis processes. Its unique combination of chlorine and fluorine atoms allows it to act as an intermediate in the production of other organic compounds, particularly those requiring halogenated aromatic structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,3,5-trichlorotrifluorobenzene is used as a building block for the synthesis of various drug molecules. Its specific halogenated structure can contribute to the development of new drugs with improved pharmacological properties, such as enhanced solubility, stability, and bioavailability.
Used in Agrochemical Industry:
1,3,5-Trichloro-2,4,6-trifluorobenzene is also utilized in the agrochemical industry for the synthesis of active ingredients in pesticides and herbicides. Its chemical properties make it suitable for the development of compounds that can effectively control pests and weeds in agricultural settings.
Used in Material Science:
In the field of material science, 1,3,5-trichlorotrifluorobenzene can be employed in the development of new materials with specific properties. Its halogenated structure can contribute to the creation of materials with improved thermal stability, chemical resistance, and other desirable characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 319-88-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 319-88:
(5*3)+(4*1)+(3*9)+(2*8)+(1*8)=70
70 % 10 = 0
So 319-88-0 is a valid CAS Registry Number.
InChI:InChI=1/C6Cl3F3/c7-1-4(10)2(8)6(12)3(9)5(1)11
319-88-0Relevant articles and documents
A 2, 4 - difluoro - 3, 5 - dichloro nitrobenzene synthesis of 1, 3, 5 - trichloro - 2, 4, 6 - trifluorobenzene
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Paragraph 0065; 0066; 0067; 0068; 0069; 0070, (2017/08/25)
The invention discloses a method for synthesizing 1,3,5-trichloro-2,4,6-trifluorobenzene from 2,4-difluoro-3,5-dichloronitrobenzene. The method comprises performing chlorination reaction on 2,4-difluoro-3,5-dichloronitrobenzene in chlorine atmosphere to obtain a chloride, and controlling the chlorination reaction temperature to 160-195 DEG C; performing nitration reaction on the chloride in a mixed acid solution of sulfuric acid and nitric acid to obtain a nitro compound, and controlling the nitration reaction temperature to 60-110 DEG C; and performing fluorination reaction on the nitro compound with a fluoride under a waterless condition so as to obtain 1,3,5-trichloro-2,4,6-trifluorobenzene, and controlling the fluorination reaction temperature to 80-200 DEG C. The product synthesized by the method is high in selectivity, and the yield and the purity of products of all steps are relatively high, and operation is simple.
Chloro- and bromo-defluorination of hexafluorobenzene and octafluorotoluene
Shipilov,Zolotkova,Igumnov
, p. 1117 - 1120 (2007/10/03)
Halo(chloro, bromo)defluorination of perfluorobenzaene and toluene efficiently occurs under the action of appropriate alkali metal halides in the presence of hexaethylguanidinium chloride in catalytic amount. The relative efficiency of halide anions and m
Perfluorocarbon fluids as solvent replacements
Chambers, Richard D.,Edwards, Andrew R.
, p. 3623 - 3627 (2007/10/03)
Perfluoroperhydrophenanthrene 1 may be used as a 'bulking agent' to minimise the problem of solvent recovery in halogen exchange ('Halex') reactions for the preparation of octafluorocyclopentene 8, and chlorofluoro-pyridine, -pyrimidine and -benzene derivatives. New 'one-pot' procedures for the syntheses of hexafluorobut-2-yne 3, octafluorobut-2-ene 11 and hexafluorocyclobutene 7 are described.
