31928-47-9

Basic information

• Product Name: 4-BROMO-2-CHLORO-1-IODOBENZENE
• Synonyms: 1-BROMO-3-CHLORO-4-IODOBENZENE;4-Bromo-3-chloro-1-iodobenzene;3-Chloro-4-iodobromobenzene;BUTTPARK 34\07-78;4-BROMO-2-CHLORO-1-IODOBENZENE;4-BROMO-2-CHLOROIODOBENZENE
• CAS NO: 31928-47-9
• Molecular Formula: C₆H₃BrClI
• Molecular Weight: 317.35
• EINECS: -0
• Product Categories: Aromatic Halides (substituted);Bromine Compounds;Chlorine Compounds;Iodine Compounds
• Mol File: 31928-47-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 35 °C
• Boiling Point: 103-105°C
• Flash Point: 103-105°C/1mm
• Appearance: /
• Density: 2.272±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.00617mmHg at 25°C
• Refractive Index: 1.6722
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive: Light Sensitive
• BRN: 2435075
• CAS DataBase Reference: 4-BROMO-2-CHLORO-1-IODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-CHLORO-1-IODOBENZENE(31928-47-9)
• EPA Substance Registry System: 4-BROMO-2-CHLORO-1-IODOBENZENE(31928-47-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-36-37
• Hazardous Substances Data: 31928-47-9(Hazardous Substances Data)

Usage

Description

4-Bromo-2-chloro-1-iodobenzene is a hydrocarbon derivative characterized by its white or colorless to yellow powder, lump, or clear liquid appearance. It is a halogenated aromatic compound with a molecular structure that includes a benzene ring substituted with a bromine, chlorine, and iodine atom at the 4th, 2nd, and 1st positions, respectively.

Uses

Used in Organic Synthesis:
4-Bromo-2-chloro-1-iodobenzene is used as an intermediate in organic synthesis for the production of various chemical compounds. Its unique structure with multiple halogen substitutions allows for a range of reactions and transformations, making it a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Bromo-2-chloro-1-iodobenzene is used as a key intermediate in the synthesis of certain drugs. Its specific functional groups and structural features enable the development of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
4-Bromo-2-chloro-1-iodobenzene is also utilized in the agrochemical industry for the synthesis of various pesticides and other crop protection agents. Its unique properties and reactivity contribute to the development of innovative products that can help improve crop yield and protect against pests and diseases.
Used in Chemical Research:
In addition to its applications in the pharmaceutical and agrochemical industries, 4-Bromo-2-chloro-1-iodobenzene is also used in chemical research for the study of reaction mechanisms, the development of new synthetic methods, and the exploration of novel chemical compounds with potential applications in various fields.

InChI:InChI=1/C6H3BrClI/c7-4-1-2-6(9)5(8)3-4/h1-3H

Upstream product

• 38762-41-3 2-chloro-4-bromoaniline 

Downstream Products

• 608131-02-8 4-bromo-2-chloro-1-cyclopropylethynyl-benzene 
• 608131-01-7 4-bromo-2-chloro-1-hex-1-ynyl-benzene 
• 740815-23-0 (4-bromo-2-chlorophenyl)(2-methylphenyl)methanol 
• 344457-87-0 {2-chloro-4-[(4-fluoro-2-methylphenyl)amino]phenyl}(2-methylphenyl)methanone 
• 740815-24-1 (4-bromo-2-chlorophenyl)(2-methylphenyl)methanone 
• 608131-11-9 [1-(4-bromo-2-chloro-benzyl)-pentyl]-p-tolyl-amine 
• 608131-12-0 [2-(4-bromo-2-chloro-phenyl)-1-cyclopropyl-ethyl]-(4-methoxy-phenyl)-amine 
• 608131-26-6 benzhydrylidene-[2-cyclopropyl-1-(4-methoxy-phenyl)-2,3-dihydro-1H-indol-6-yl]-amine 
• 608131-25-5 benzhydrylidene-(2-butyl-1-p-tolyl-2,3-dihydro-1H-indol-6-yl)-amine 
• 608131-24-4 Benzhydrylidene-{3-chloro-4-[2-cyclopropyl-2-(4-methoxy-phenylamino)-ethyl]-phenyl}-amine 
• 608131-23-3 Benzhydrylidene-[3-chloro-4-(2-p-tolylamino-hexyl)-phenyl]-amine 
• 606144-02-9 methyl 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-1-methyl-1H-benzimidazole-6-carboxylate 
• 918321-22-9 6-(4-bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid Na salt 

Relevant articles and documents

Discovery of 5-(2-chloro-4′-(1H-imidazol-1-yl)-[1,1′-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD

Endogenous nitrosothiols (SNOs) including S-nitrosoglutathione (GSNO) serve as reservoir for bioavailable nitric oxide (NO) and mediate NO-based signaling, inflammatory status and smooth muscle function in the lung. GSNOR inhibition increases pulmonary GS