32022-28-9

Basic information

• Product Name: 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate
• Synonyms: 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate
• CAS NO: 32022-28-9
• Molecular Formula: C₁₃H₁₆O₅
• Molecular Weight: 252.26314
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 32022-28-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 330.2±32.0 °C(Predicted)
• Appearance: /
• Density: 1.144±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Chloroform, DMSO
• CAS DataBase Reference: 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate(32022-28-9)
• EPA Substance Registry System: 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate(32022-28-9)

Safety Data

• Hazardous Substances Data: 32022-28-9(Hazardous Substances Data)

Usage

Description

4-(Acetyloxy)-3-Methoxybenzenethanol Acetate, also known as 4-Hydroxy-3-methoxyphenethyl Alcohol Diacetate, is a derivative of Tyrosol (T947800), a phenolic antioxidant that can be extracted from olive oil. 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate is characterized by its acetate functional groups and hydroxyl and methoxy substituents on the benzene ring, which contribute to its unique chemical properties and potential applications.

Uses

Used in Pharmaceutical Industry:
4-(Acetyloxy)-3-Methoxybenzenethanol Acetate is used as a pharmaceutical compound for its antioxidant properties. 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate's ability to scavenge free radicals and protect cells from oxidative damage makes it a promising candidate for the development of drugs targeting various diseases associated with oxidative stress, such as neurodegenerative disorders and cardiovascular diseases.
Used in Cosmetic Industry:
In the cosmetic industry, 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate is used as an active ingredient for its antioxidant and anti-aging effects. Its ability to neutralize free radicals and protect the skin from environmental stressors can help reduce the signs of aging, such as wrinkles and fine lines, and maintain the skin's overall health and appearance.
Used in Food Industry:
4-(Acetyloxy)-3-Methoxybenzenethanol Acetate is used as a natural antioxidant in the food industry to extend the shelf life of products and maintain their quality. Its ability to protect food products from oxidation and spoilage can help reduce the need for synthetic additives and preservatives, making it a valuable component in the development of healthier and more natural food products.
Used in Research Applications:
In research settings, 4-(Acetyloxy)-3-Methoxybenzenethanol Acetate is used as a chemical probe and analytical standard for studying the biological activities and mechanisms of action of phenolic antioxidants. Its unique structure and properties make it a valuable tool for understanding the role of antioxidants in various biological processes and their potential therapeutic applications.

Upstream product

• 2380-78-1 homovanillyl alcohol 
• 108-24-7 acetic anhydride 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 196081-78-4 3-bromo-4-hydroxyphenylethyl alcohol 

Downstream Products

• 69039-02-7 2-(3,4-dihydroxyphenyl)ethyl acetate 

Relevant articles and documents

Antioxidant and Biological Activities of Hydroxytyrosol and Homovanillic Alcohol Obtained from Olive Mill Wastewaters of Extra-Virgin Olive Oil Production

Some constituents of the Mediterranean diet, such as extra-virgin olive oil (EVOO) contain substances such as hydroxytyrosol (HT) and its metabolite homovanillic alcohol (HA). HT has aroused much interest due to its antioxidant activity as a radical scavenger, whereas only a few studies have been made on the HA molecule. Both chemical synthesis and extraction techniques have been developed to obtain these molecules, with each method having its advantages and drawbacks. In this study, we report the use of tyrosol from olive mill wastewaters as a starting molecule to synthesize HT and HA, using a sustainable procedure characterized by high efficiency and low cost. The effects of HT and HA were evaluated on two cell lines, THP-1 human leukemic monocytes and L-6 myoblasts from rat skeletal muscle, after treating the cells with a radical generator. Both HT and HA efficiently inhibited ROS production. In particular, HT inhibited the proliferation of the THP-1 leukemic monocytes, while HA protected L-6 myoblasts from cytotoxicity.

Tunable microwave-assisted method for the solvent-free and catalyst-free peracetylation of natural products

Background: The peracetylation is a simple chemical modification that can be used to enhance the bioavailability of hydrophilic products and to obtain safe and stable pro-drugs. Results: A totally green, solvent-free and catalyst-free microwave (MW)-assisted method for peracetylation of natural products such as oleuropein, alpha-hederin, quercetin and rutin is presented. By simply tuning the MW heating program, polyols with chemical diverse -OH groups or thermolabile functionalities can be peracetylated to improve the biological activity without degradation of the natural starting molecules. An evaluation of the process greenness was performed. Conclusion: The method is potentially universally applicable for green acetylation of hydrophilic biological molecules, potentially easily scalable for industrial applications, including pharmaceutical, cosmetic and food industry.

Expedient synthesis of hydroxytyrosol and its esters

An efficient and friendly method for obtaining hydroxytyrosol from tyrosol, a component of olive waste, is reported. Hydroxytyrosol also may be obtained in the form of enzymatically convertible precursors (e.g., hydroxytyrosyl acetate), thus increasing the stability of the active principle. Copyright Taylor & Francis Group, LLC.