3208-40-0 Usage
Description
2-(3-PHENYLPROPYL)TETRAHYDROFURAN is an organic compound characterized by its sweet, fruity odor and a honey-like, sweet flavor. It is a tetrahydrofuran derivative with a phenylpropyl group attached to the second carbon, which contributes to its unique sensory properties.
Uses
Used in Flavor and Fragrance Industry:
2-(3-PHENYLPROPYL)TETRAHYDROFURAN is used as a flavoring agent for its sweet, fruity odor and honey-like, sweet taste. It is particularly suitable for enhancing the flavor profiles of various food products, making them more appealing to consumers.
Used in Cosmetics and Personal Care Industry:
In the cosmetics and personal care industry, 2-(3-PHENYLPROPYL)TETRAHYDROFURAN is used as a fragrance ingredient. Its sweet, fruity scent can be incorporated into a wide range of products, such as perfumes, lotions, and shampoos, to provide a pleasant and long-lasting aroma.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, due to its unique chemical structure and sensory properties, 2-(3-PHENYLPROPYL)TETRAHYDROFURAN could potentially be used in the pharmaceutical industry for the development of drugs targeting specific receptors or pathways related to its sensory characteristics. Further research would be required to explore this application.
Preparation
From β-[2-(5-phenyl furyl)]-propionic acid butyl ester by catalytic hydrogenation with copper chromite under pressure
and subsequent ring closure by heating the intermediate, 7-phenylheptan-1,4-diol, in the presence of Al2O3.
Check Digit Verification of cas no
The CAS Registry Mumber 3208-40-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,0 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3208-40:
(6*3)+(5*2)+(4*0)+(3*8)+(2*4)+(1*0)=60
60 % 10 = 0
So 3208-40-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O/c1-2-6-12(7-3-1)8-4-9-13-10-5-11-14-13/h1-3,6-7,13H,4-5,8-11H2
3208-40-0Relevant articles and documents
Alkylation of acetals using manganate-BF3·OEt2 mixed reagent
Hojo, Makoto,Ushioda, Nobuo,Hosomi, Akira
, p. 4499 - 4501 (2004)
A mixture of 'R3MnMgBr' and BF3·OEt 2 prepared in advance only by stirring both reagents in ether converted acetals to alkylation products, where an alkoxy group of acetals was substituted by the alkyl group of manganese reagent used. Ketals also reacted with the 'mixed reagent' to afford the corresponding alkylation products in high yield. α-Alkoxy-substituted cyclic ethers and acetoxy-substituted cyclic ethers were selectively converted to ring-opening alkylation products and α-alkyl-substituted cyclic ethers, respectively.
The Combination of Benzaldehyde and Nickel-Catalyzed Photoredox C(sp3)?H Alkylation/Arylation
Zhang, Lumin,Si, Xiaojia,Yang, Yangyang,Zimmer, Marc,Witzel, Sina,Sekine, Kohei,Rudolph, Matthias,Hashmi, A. Stephen K.
supporting information, p. 1823 - 1827 (2019/01/14)
Herein we report a highly selective photoredox C(sp3)?H alkylation/arylation of ethers through the combination of a photo-organocatalyst (benzaldehyde) and a transition-metal catalyst (nickel). This method provides a simple and general strategy for the C(sp3)?H alkylation/arylation of ethers. A selective late-stage modification of (?)-ambroxide has also been conducted to demonstrate the applicability of the method.