321657-85-6

Basic information

• Product Name: (E/Z)-N-(1-nitro-2-naphthylidene)-4-cyanoaniline
• Synonyms: (E/Z)-N-(1-nitro-2-naphthylidene)-4-cyanoaniline
• CAS NO: 321657-85-6
• Molecular Weight: 301.304
• Mol File: 321657-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E/Z)-N-(1-nitro-2-naphthylidene)-4-cyanoaniline(CAS DataBase Reference)
• NIST Chemistry Reference: (E/Z)-N-(1-nitro-2-naphthylidene)-4-cyanoaniline(321657-85-6)
• EPA Substance Registry System: (E/Z)-N-(1-nitro-2-naphthylidene)-4-cyanoaniline(321657-85-6)

Safety Data

• Hazardous Substances Data: 321657-85-6(Hazardous Substances Data)

Upstream product

• 101327-84-8 1-nitronaphthalene-2-carboxaldehyde 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 6321-94-4 N-(4-cyanophenyl)formamide 

Relevant articles and documents

An approach to fused pyrimidine derivatives via Schiff bases of aromatic ortho-nitrocarbaldehydes. An investigation of substituent effects on the reaction course

The synthesis of fused pyrimidines from the Schiff bases of aromatic ortho-nitrocarbaldehydes is reported. The Schiff bases after selective reduction of the nitro group on 10% Pd/C, followed by condensation of the amines formed with orthoesters, are transformed to the corresponding imidates. Heating of the latter in a sealed tube with an excess of ammonia (or with ammonia in ethanol) gives fused pyrimidines. The influence of various substituents in the aromatic ring of the imine moiety of the Schiff bases on the overall yield of fused pyrimidine derivatives has been investigated. Moderate electron-withdrawing groups gave the best results.