32207-46-8Relevant articles and documents
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 2. Probing the indeno ring substituent pattern
Nugiel, David A.,Vidwans, Anup,Etzkorn, Anna-Marie,Rossi, Karen A.,Benfield, Pamela A.,Burton, Catherine R.,Cox, Sarah,Doleniak, Deborah,Seitz, Steven P.
, p. 5224 - 5232 (2007/10/03)
We disclose a novel series of indenopyrazole-based cyclin-dependent kinase (CDK) inhibitors. Kinetic experiments confirmed our initial molecular modeling studies that the compounds are competitive with respect to adenosine 5′-triphosphate (ATP) and bind i
