32380-83-9

Basic information

• Product Name: Phenol, 4-chloro-2-(1H-indol-2-yl)-
• CAS NO: 32380-83-9
• Molecular Formula: C14H10ClNO
• Molecular Weight: 243.692
• Mol File: 32380-83-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 4-chloro-2-(1H-indol-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-chloro-2-(1H-indol-2-yl)-(32380-83-9)
• EPA Substance Registry System: Phenol, 4-chloro-2-(1H-indol-2-yl)-(32380-83-9)

Safety Data

• Hazardous Substances Data: 32380-83-9(Hazardous Substances Data)

Upstream product

• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 100-63-0 phenylhydrazine 
• 67338-35-6 4-chloro-2-[1-(2-phenylhydrazin-1-ylidene)ethyl]phenol 

Downstream Products

• 1421355-79-4 4-chloro-2-(1H-indol-2-yl)phenyl trifluoromethanesulfonate 
• 1421355-92-1 4-chloro-2-(3-(trifluoromethylsulfonyl)-1H-indol-2-yl)phenol 

Relevant articles and documents

One-Pot Highly Regioselective Synthesis of Indole-Fused Pyridazino[4,5- b ][1,4]benzoxazepin-4(3 H)-ones by a Smiles Rearrangement

A simple and convenient synthesis of indole-fused pyridazino[4,5- b ][1,4]benzoxazepin-4(3 H)-ones is described. A range of 2-(1 H -indol-2-yl)phenols and 4,5-dichloropyridazin-3-ones are compatible with this reaction. A Smiles rearrangement is proposed as a key step in the highly regioselective construction of the products. The easy availability of the starting materials makes this an appealing method in organic synthesis.

Remote anionic fries rearrangement of sulfonates: Regioselective synthesis of indole triflones

An unusual NaH-mediated remote anionic 1,5-thia-Fries rearrangement reaction was developed. This method provides an efficient approach for the regioselective synthesis of not only 2-(2-hydroxyphenyl)-3-indole triflones but also related 3-sulfonylindoles.