325807-61-2Relevant articles and documents
New 2H-chromene-3-carboxamide derivatives: Design, synthesis and use as inhibitors of hMAO
Pan, Zhi-Xiang,He, Xu,Chen, Yan-Yan,Tang, Wen-Jian,Shi, Jing-Bo,Tang, Yu-Lan,Song, Bao-An,Li, Jun,Liu, Xin-Hua
, p. 278 - 284 (2014/05/20)
A series new 2H-chromene-3-carboxamide derivatives 4a-4t were synthesized and evaluated as monoamine oxidase A and B (MAO-A and MAO-B) inhibitors. Among them, compound 4d (IC50 = 0.93 μM, IC50 iproniazid = 7.80 μM) showed the most ac