3260-90-0

Basic information

• Product Name: 4-Chloro-3(2H)-benzofuranone
• Synonyms: 4-Chloro-3(2H)-benzofuranone;4-Bromo-3-Benzofuranone;4-Chlorobenzofuran-3(2H)-one
• CAS NO: 3260-90-0
• Molecular Formula: C₈H₅ClO₂
• Molecular Weight: 168.5771
• Mol File: 3260-90-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 322.581°C at 760 mmHg
• Flash Point: 148.892°C
• Appearance: /
• Density: 1.743g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Chloro-3(2H)-benzofuranone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-3(2H)-benzofuranone(3260-90-0)
• EPA Substance Registry System: 4-Chloro-3(2H)-benzofuranone(3260-90-0)

Safety Data

• Hazardous Substances Data: 3260-90-0(Hazardous Substances Data)

Usage

General Description

4-Chloro-3(2H)-benzofuranone is a chemical compound with the molecular formula C8H5ClO2. It is a chlorinated derivative of benzofuranone and is commonly used in the synthesis of pharmaceuticals and agrochemicals. 4-Chloro-3(2H)-benzofuranone is also known for its antibacterial and antifungal properties, making it a valuable ingredient in the production of disinfectants and pesticides. Additionally, it has been found to exhibit antioxidant and anti-inflammatory properties, which may have potential applications in the development of new drugs for treating various diseases. However, it is important to handle 4-Chloro-3(2H)-benzofuranone with caution as it is a hazardous chemical that can cause skin and eye irritation, and should only be used in controlled laboratory settings by trained professionals.

InChI:InChI=1/C8H5BrO2/c9-5-2-1-3-7-8(5)6(10)4-11-7/h1-3H,4H2

Upstream product

• 18362-30-6 2-chloro-6-hydroxybenzaldehyde 

Relevant articles and documents

A Hg(OTf)2-Catalyzed Enolate Umpolung Reaction Enables the Synthesis of Coumaran-3-ones and Indolin-3-ones

The potential of mercury catalysis has been extended to the arena of enolate umpolung reactions for the first time by the generation of enolonium species via Hg(OTf)2-catalyzed N-oxide addition to alkynes. The enolonium species formed can undergo intramolecular nucleophilic attack by hydroxyl or amino groups, leading to the synthesis of various coumaran-3-ones and indolin-3-ones.

Synthesis of some griseofulvin analogues.

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