32631-29-1

Basic information

• Product Name: 4-AMINO-4'-CHLORO DIPHENYL SULFIDE
• Synonyms: BENZENAMINE, 4-[(4-CHLOROPHENYL)THIO]-;4-AMINO-4'-CHLORO DIPHENYL SULFIDE;4-AMINO-4''-CHLORO DIPHENYL SULFIDE 98.0%MIN;4-Amino-4'-chloro di;4-chloro-4′-aminodiphenyl sulfide;4-((4-Chlorophenyl)thio)aniline
• CAS NO: 32631-29-1
• Molecular Formula: C₁₂H₁₀ClNS
• Molecular Weight: 235.73
• Mol File: 32631-29-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 54.7-56.5 °C
• Boiling Point: 420.1 °C at 760 mmHg
• Flash Point: 207.9 °C
• Appearance: /
• Density: 1.31 g/cm³
• Vapor Pressure: 2.89E-07mmHg at 25°C
• Refractive Index: 1.683
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.49±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-4'-CHLORO DIPHENYL SULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-4'-CHLORO DIPHENYL SULFIDE(32631-29-1)
• EPA Substance Registry System: 4-AMINO-4'-CHLORO DIPHENYL SULFIDE(32631-29-1)

Safety Data

• Hazardous Substances Data: 32631-29-1(Hazardous Substances Data)

Usage

General Description

4-Amino-4'-chloro diphenyl sulfide is a chemical compound with the molecular formula C12H10ClNS. It is a white to off-white solid that is commonly used as an intermediate in the production of dyes, pharmaceuticals, and other organic compounds. 4-AMINO-4'-CHLORO DIPHENYL SULFIDE is known for its high melting point and its insolubility in water, but it is soluble in organic solvents such as ethanol and acetone. 4-Amino-4'-chloro diphenyl sulfide is also known for its potential as a mutagen, with studies suggesting that it may induce mutations in bacteria and mammalian cells. Due to its potential mutagenic properties, it is important to handle this chemical with care and to follow proper safety protocols when working with it in a laboratory setting.

InChI:InChI=1/C12H10ClNS/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,14H2

Upstream product

• 21969-11-9 1-(4-chlorophenylthio)-4-nitrobenzene 
• 100-00-5 4-chlorobenzonitrile 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 62-53-3 aniline 
• 42839-20-3 1-((4-chlorophenyl)thio)pyrrolidine-2,5-dione 
• 106-54-7 p-Chlorothiophenol 
• 106-40-1 4-bromo-aniline 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 141794-15-2 1-[4-(4-chloro-phenylsulfanyl)-phenyl]-biguanide 
• 54457-32-8 1-[4-(4-Chloro-phenylsulfanyl)-phenyl]-3-propyl-urea 
• 58290-76-9 1-[4-(4-Chloro-phenylsulfanyl)-phenyl]-3-((Z)-3-ethoxy-acryloyl)-urea 
• 37930-90-8 4-(4-Chlorphenylthio)-trifluormethansulfonanilid 
• 54457-30-6 1-[4-(4-Chloro-phenylsulfanyl)-phenyl]-3-methyl-urea 
• 54457-31-7 1-(4-((4-chlorophenyl)thio)phenyl)-3-ethylurea 
• 32631-18-8 Cyclopropanecarboxylic acid [4-(4-chloro-phenylsulfanyl)-phenyl]-amide 
• 36161-08-7 4-Chloracetylamino-4'-chlordiphenylsulfid 
• 77711-78-5 Acetic acid 2-[4-(4-chloro-phenylsulfanyl)-phenylcarbamoyl]-phenyl ester 
• 77711-37-6 N-[4-(4-Chloro-phenylsulfanyl)-phenyl]-N-methyl-formamide 
• 93819-81-9 p-Phenylen-bis-<4-chlor-phenylsulfid> 
• 77711-82-1 N-[2-(4-Chloro-phenylsulfanyl)-phenyl]-2-diethylamino-acetamide 
• 77711-64-9 N-[4-(4-Chloro-phenylsulfanyl)-phenyl]-2-morpholin-4-yl-acetamide 
• 77711-68-3 N-[4-(4-Chloro-phenylsulfanyl)-phenyl]-2-diethylamino-N-methyl-acetamide 

Relevant articles and documents

Iodine/DMSO-Promoted Selective Direct Arylthiation of Anilines with Thiols under Metal-Free Conditions

An iodine-promoted divergent thiolation of unprotected anilines with thiols for the synthesis of sulfide anilines has been described. The combinational use of I2 and DMSO played an important role to realize this kind of transformation without the aid of a

CoII immobilized on an aminated magnetic metal-organic framework catalyzed C-N and C-S bond forming reactions: A journey for the mild and efficient synthesis of arylamines and arylsulfides

In this work, we report a simple and versatile method for the modification of a metal-organic framework (NH2-MIL53(Al)) in a step-wise manner. To characterize the synthesized nanostructured catalyst, a variety of spectroscopic and microscopic techniques including FT-IR, XRD, BET, TEM, FE-SEM, EDX, EDX-mapping, TGA, XPS, VSM, ICP-OES and CHN have been employed. Fe3O4@AMCA-MIL53(Al)-NH2-CoII NPs, which benefit from small nanocrystalline size (10-30 nm, according to the XRD and TEM data) in combination with the coexistence of magnetic nanoparticles, a metal-organic framework, and cobalt species, were found to be an excellent environment catalyst to promote the C-N and C-S cross coupling reactions. A wide range of functional substrates including electron-withdrawing and electron-donating aryl halides underwent the coupling reaction with aromatic/heteroaromatic/benzylic and aliphatic amines and sulfides. The results demonstrated that the yields of the target products were good to excellent and the catalyst can be recycled for at least seven recycling runs without a discernible decrease in its catalytic activity. Furthermore, the heterogeneity studies (such as hot filtration and poisoning tests) efficiently confirmed that the as-synthesized nanostructured catalyst is heterogeneous and completely stable under the reaction conditions. We hope that our study inspires more interest in designing novel catalysts based on using low-cost metal ions (such as cobalt) in the field of cross coupling reactions.

Metal-Free Iodine-Catalyzed Direct Arylthiation of Substituted Anilines with Thiols

Iodine-catalyzed direct arylthiation of substituted anilines for the synthesis of various diaryl sulfides has been developed under metal- and solvent-free conditions. The present method uses readily available thiols as the arylthiation reagents, and envir