32723-48-1

Basic information

• Product Name: 3(2H)-Pyridazinone, 4-methyl-6-phenyl-, hydrazone
• CAS NO: 32723-48-1
• Molecular Formula: C11H12N4
• Molecular Weight: 200.243
• Mol File: 32723-48-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone, 4-methyl-6-phenyl-, hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone, 4-methyl-6-phenyl-, hydrazone(32723-48-1)
• EPA Substance Registry System: 3(2H)-Pyridazinone, 4-methyl-6-phenyl-, hydrazone(32723-48-1)

Safety Data

• Hazardous Substances Data: 32723-48-1(Hazardous Substances Data)

Upstream product

• 28657-39-8 3-chloro-4-methyl-6-phenylpyridazine 
• 13300-09-9 4-methyl-6-phenylpyridazin-3(2H)-one 

Downstream Products

• 83506-43-8 N-(4-Methyl-6-phenyl-pyridazin-3-yl)-N'-[1-phenyl-meth-(E)-ylidene]-hydrazine 
• 105537-56-2 2-(carboxymethyl)-3-amino-4-methyl-6-phenylpyridazinium acetate 
• 105537-95-9 6-Amino-1-(3-ethoxycarbonyl-1-methyl-propyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-93-7 ethyl ester of 2-(5-carboxypentyl)-3-amino-4-methyl-6-phenylpyridazinium bromide 
• 105537-94-8 6-Amino-1-(3-ethoxycarbonyl-butyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-92-6 6-Amino-1-(4-ethoxycarbonyl-butyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-61-9 6-Amino-1-(3-carboxy-1-methyl-propyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-54-0 2-(3-carbethoxypropyl)-3-amino-4-methyl-6-phenylpyridazinium bromide 
• 105537-60-8 6-Amino-1-(3-carboxy-butyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105538-10-1 6-Amino-1-(2-ethoxycarbonyl-ethyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-59-5 2-(5-carboxypentyl)-3-amino-4-methyl-6-phenylpyridazinium bromide 
• 105537-57-3 6-Amino-1-(2-carboxy-ethyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105562-24-1 6-Amino-1-(3-carbamoyl-propyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-55-1 6-Amino-1-(3-cyano-propyl)-5-methyl-3-phenyl-pyridazin-1-ium; bromide 

Relevant articles and documents

FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Reactions of 3-Chloropyridazines with Some Nucleophilic Reagents

3-Chloro-6-phenylpyridazine (1a) and its 4-methyl derivative (1b) react with sodamide, hydrazines, 3-aminopyridazines and phenothiazine in polar and non-polar solvents as well as by fusion to give different products.The structures assigned to the products have been confirmed by their IR spectra.