3279-62-7

Basic information

• Product Name: 2,4-dichlorophenyl diethyl phosphate
• Synonyms: 2,4-Dichlorophenyl diethyl phosphate; 2,4-Dichlorphenyl-diethylphosphat; Phosphate de 2,4-dichlorophényle et de diéthyle; phosphoric acid, 2,4-dichlorophenyl diethyl ester
• CAS NO: 3279-62-7
• Molecular Formula: C₁₀H₁₃Cl₂O₄P
• Molecular Weight: 299.0876
• Mol File: 3279-62-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 326.6°C at 760 mmHg
• Flash Point: 208.5°C
• Density: 1.336g/cm³
• Vapor Pressure: 0.000405mmHg at 25°C
• Refractive Index: 1.51
• CAS DataBase Reference: 2,4-dichlorophenyl diethyl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichlorophenyl diethyl phosphate(3279-62-7)
• EPA Substance Registry System: 2,4-dichlorophenyl diethyl phosphate(3279-62-7)

Safety Data

• Hazardous Substances Data: 3279-62-7(Hazardous Substances Data)

Usage

Type of chemical

organophosphate pesticide

Usage

widely used in agriculture to control a variety of crop pests

Toxicity

highly toxic

Adverse health effects in humans

nausea, headaches, dizziness, and can be lethal in high doses

Environmental impact

harmful to non-target species, including birds, fish, and other wildlife, and can cause environmental contamination of water and soil

Health concerns

known endocrine disruptor, linked to reproductive and developmental issues, and cancer

Global usage

continues to be used in many countries with restrictions and regulations in place.

Upstream product

• 762-04-9 phosphonic acid diethyl ester 
• 120-83-2 2,4-dichlorophenol 
• 64-17-5 ethanol 
• 19430-75-2 2,4-dichlorophenylphosphorodichloridate 
• 814-49-3 diethyl chlorophosphate 
• 97-17-6 dichlofenthion 

Relevant articles and documents

Oxidation of organophosphorus pesticides for the sensitive detection by a cholinesterase-based biosensor

A potentiometric flow injection-type biosensor developed in our laboratory was used for the determination of organophosphorus pesticides (OPs). The principle of the biosensor is that the degree of inhibition of a sensor enzyme by an OP is dependent on the concentration of the pesticide. The sensor system consisted of a reactor with acetylcholinesterase (AChE) immobilized on a controlled pore glass and a detector with a tubular H+-selective membrane electrode. In order to examine the possibility of enhancing the sensitivity of the sensor by converting OPs to oxidized forms (stronger inhibitors), a comparison of the degree of enzyme inhibition by OPs at 10-6 M before and after their oxidation was made. All of the ten pesticides tested exhibited greater inhibitory power toward the sensor enzyme following oxidation. All of the oxidized pesticides at 10-6 M inhibited the sensor enzyme to a considerable degree, demonstrating the utility of the developed method for the class-specific determination of OPs. A calibration curve for diazinon, over the concentration range of 10-11-10-4 M, was obtained. The lower detection limit was 2 × 10-10 M. Treatment of the inhibited enzyme with pyridine-2-aldoxime restored the enzyme to near full activity, allowing repeated use of the sensor,

1,3-CARBANIONISCHE UMLAGERUNGEN: REAKTIONEN VON PHOSPHORSAEURE-o-HALOARYLESTERN MIT METALLEN ZU ARYLPHOSPHONSAEUREDERIVATEN

o-Bromoaryl esters of phosphoric acid react with magnesium to give arene phosphonic acid derivatives via intermediate Grignard compounds.Similar metallation rearrangement processes may be achieved in the case of o-chloroaryl esters if sodium is applied as