329-59-9 Usage
Description
Methyl 4-fluoro-3-nitrobenzoate is an organic compound that features a methyl ester group attached to a benzene ring, which is substituted with a fluorine atom at the 4-position and a nitro group at the 3-position. This chemical structure endows it with specific reactivity and properties that make it suitable for various applications in chemical synthesis and related fields.
Uses
Used in Chemical Synthesis:
Methyl 4-fluoro-3-nitrobenzoate is used as a key intermediate in the synthesis of complex organic molecules. Its unique combination of functional groups allows it to participate in a variety of chemical reactions, facilitating the formation of new compounds with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 4-fluoro-3-nitrobenzoate is used as a building block for the synthesis of pharmaceutical compounds. Its reactivity and the presence of electron-withdrawing groups make it a valuable component in the development of new drugs with improved therapeutic properties.
Used in the Preparation of Dimethyl 3-nitro-3',4-oxydibenzoate:
Methyl 4-fluoro-3-nitrobenzoate is specifically used to prepare dimethyl 3-nitro-3',4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester. This reaction is an example of how Methyl 4-fluoro-3-nitrobenzoate can be utilized in the synthesis of specific target molecules, which may have applications in various fields such as materials science, pharmaceuticals, or agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 329-59-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 9 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 329-59:
(5*3)+(4*2)+(3*9)+(2*5)+(1*9)=69
69 % 10 = 9
So 329-59-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H6FNO4/c1-14-8(11)5-2-3-6(9)7(4-5)10(12)13/h2-4H,1H3
329-59-9Relevant articles and documents
Regioselective Synthesis of Angular Isocoumarinselenazoles: A Benzoselenazole-directed, Site-specific, Ruthenium-catalyzed C(sp2)-H Activation
Dhole, Sandip,Liao, Jen-Yu,Kumar, Sunil,Salunke, Deepak B.,Sun, Chung-Ming
, p. 942 - 950 (2018)
The synthesis of new, angular isocoumarinselenazoles is described, which involves the construction of 2-amino benzoselenazoles and their regioselective C2N-alkylation and alkyne insertion. An expeditious and metal-free synthesis of 2-aminobenzoselenazoles
Preparation method of 3-acetylindole BRPF1 inhibitor and use of 3-acetylindole BRPF1 inhibitor
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Paragraph 0077-0080; 0134-0136, (2020/03/03)
The invention relates to a 3-acetylindole compound of a novel structure shown in a formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate or a solvate thereof, a preparation method of the compound, a pharmaceutical composition containing a therapeutically effective dose of the compound, and use thereof as a protein tyrosine kinase inhibitor, especially as a bromine-containing area PHD zinc finger protein 1 (BRPF1) inhibitor, in the prevention or treatment of disease benefited from the inhibition of BRPF1.
EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPY
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Paragraph 0379, (2020/07/07)
Antisense oligomers complementary to a selected target site in the human dystrophin gene to induce exon 50 skipping are described. In various aspects, antisense oligomers are described according to Formula (I): or a pharmaceutically acceptable salt thereo