3296-07-9Relevant articles and documents
Synthesis, antiproliferative, docking and DFT studies of benzimidazole derivatives as EGFR inhibitors
Alam, Mohammad Mahboob,Alzahrani, Hessah Abdullah,Elhenawy, Ahmed A.,Malebari, Azizah M.,Nazreen, Syed
, (2022/01/04)
In the present work, new benzimidazole linked 1,2,3-triazole hybrids have been synthesized and screened for antiproliferative and EGFR kinase inhibitory activities.The structures of these hybrids were elucidated using IR, NMR, mass spectrometry and elemen
Design, synthesis and effect of triazole derivatives against some toxic activities of Bothrops jararaca venom
da Silva, Aldo R.,da Silva, Ana Cláudia R.,Donza, Marcio Roberto H.,de Aquino, Gabriel Alves S.,Kaiser, Carlos R.,Sanchez, Eladio F.,Ferreira, Sabrina B.,Fuly, André L.
, p. 182 - 195 (2020/10/26)
According to the World Health Organization, snakebite envenoming is a neglected disease that affects around 5.4 million people worldwide each year. In Brazil, in 2019 there were 29,000 cases of accidents, with 104 deaths. The genus Bothrops was responsibl
New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives
Ciupak, Olga,Da?ko, Mateusz,Biernacki, Karol,Rachon, Janusz,Mas?yk, Maciej,Kubiński, Konrad,Martyna, Aleksandra,Demkowicz, Sebastian
, p. 238 - 247 (2020/12/18)
In the present work, we report a new class of potent steroid sulphatase (STS) inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives. Within the set of new STS inhibitors, 6-(1-(1,2,3-trifluorophenyl)-1H-1,2,3-triazol
