32998-03-1

Basic information

• Product Name: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE
• Synonyms: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE
• CAS NO: 32998-03-1
• Molecular Formula: C₅H₅Cl₂N₃
• Molecular Weight: 178.02
• Mol File: 32998-03-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 186 °C
• Boiling Point: 314.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.492±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -0.77±0.10(Predicted)
• CAS DataBase Reference: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE(32998-03-1)
• EPA Substance Registry System: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE(32998-03-1)

Safety Data

• Hazardous Substances Data: 32998-03-1(Hazardous Substances Data)

Usage

General Description

2,6-Dichloro-N-methyl-4-pyrimidinamine is a chemical compound with the molecular formula C5H5Cl2N3. It is a derivative of pyrimidine and is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. This chemical is a white solid that is soluble in organic solvents and has a molecular weight of 164.98 g/mol. 2,6-Dichloro-N-methyl-4-pyrimidinamine has potential applications in the development of new drugs and agrochemicals due to its unique properties and structure. It is important to handle this chemical with care and follow proper safety protocols when working with it in a laboratory or industrial setting.

Upstream product

• 3764-01-0 2,4,6-trichloropyrimidine 
• 64-17-5 ethanol 
• 74-89-5 methylamine 

Downstream Products

• 65766-32-7 6-chloro-N-methylpyrimidin-4-amine 
• 856974-71-5 (2,6-bis-benzyloxy-pyrimidin-4-yl)-methyl-amine 
• 162265-98-7 2,6-dibenzyloxy-4-pyrimidine 
• 34284-87-2 6-(methylamino)pyrimidine-2,4(1H,3H)-dione 
• 856289-68-4 N²,N⁴-dimethyl-pyrimidine-2,4-diyldiamine 

Relevant articles and documents

Substituted pyridine and pyrimidine derivatives and their use in treating viral infections

The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

NOVEL SEH INHIBITORS AND THEIR USE

The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme.

Simplified analogues of acyclonucleosides. Synthesis of 6-[N-alkyl-N-(4- hydroxybutyl)amino]pyrimidine derivatives

The synthesis of some 6-alkylaminopyrimidine derivatives bearing a 4- hydroxybutyl chain as sugar mimic is described. These new compounds can be regarded as simplified, ring-opened analogues of purine acyclonucleosides.