32999-37-4 Usage
General Description
1,2,3,4-Tetrahydro-isoquinolin-8-ol, also known as THIQ-8-ol, is a chemical compound that belongs to the class of isoquinolinols. It is a substituted isoquinoline derivative with a tetrahydroisoquinoline core structure and a hydroxyl functional group at the 8 position. 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL has been studied for its potential pharmacological properties, including its role as an intermediate in the synthesis of bioactive compounds and pharmaceuticals. Additionally, 1,2,3,4-Tetrahydro-isoquinolin-8-ol has been investigated for its neuroprotective and antioxidant properties. Its chemical structure and reactivity make it a versatile building block for the synthesis of various organic compounds with potential applications in medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 32999-37-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,9 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 32999-37:
(7*3)+(6*2)+(5*9)+(4*9)+(3*9)+(2*3)+(1*7)=154
154 % 10 = 4
So 32999-37-4 is a valid CAS Registry Number.
32999-37-4Relevant articles and documents
Tyrosine Kinase Inhibitor And Uses Thereof
-
Paragraph 0455-0456, (2017/05/15)
Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.
Effect of pH on the Regioselectivity of Pictet-Spengler Reactions of 3-Hydroxyphenethylamines with Formaldehyde and Acetaldehyde
Bates, Hans A.,Bagheri, Kourosh,Vertino, Paula M.
, p. 3061 - 3063 (2007/10/02)
-
