33038-29-8Relevant articles and documents
Synthesis of oxacalothrixin B and its analogues involving iodine/TBHP-mediated electrocyclization
Ramalingam, Bose Muthu,Mohanakrishnan, Arasambattu K.
, p. 2919 - 2922 (2017/07/11)
The total synthesis of oxacalothrixins, an isostere of biologically important carbazoloquinone alkaloid, calothrixin B was achieved from 2-acetyl-3-methylbenzofuran. An iodine/TBHP-mediated oxidative cyclization of benzofuranyl-enamine has been employed as a key step to synthesize, the crucial intermediate 1-hydroxy dibenzofurancarbaldehyde. The latter upon reductive cyclization followed by PIDA-mediated oxidation furnished oxacalothrixin B and its analogues.
Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones: Excellent substrates for NAD(P)H:quinone oxidoreductase 1
Newsome, Jeffery J.,Hassani, Mary,Swann, Elizabeth,Bibby, Jane M.,Beall, Howard D.,Moody, Christopher J.
, p. 2999 - 3009 (2013/07/05)
A series of heterocyclic quinones based on benzofuran, benzothiophene, indazole and benzisoxazole has been synthesized, and evaluated for their ability to function as substrates for recombinant human NAD(P)H:quinone oxidoreductase (NQO1), a two-electron reductase upregulated in tumor cells. Overall, the quinones are excellent substrates for NQO1, approaching the reduction rates observed for menadione.
Functionalized fulgides and fluorophore-photoswitch conjugates
Struebe, Frank,Rath, Susann,Mattay, Jochen
, p. 4645 - 4653 (2011/10/03)
Various fulgides based on benzofuryl and indolyl core units with versatile functionalities were synthesized. Substitution at the phenylic site shows only small effects on the photochromic properties compared to the parent compounds 30 and 31. Fulgide-dye
