33159-27-2

Basic information

• Product Name: Ecabet
• Synonyms: Ecabet;12-Sulfodehydroabietic acid;1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, (1R,4aS,10aR)-;1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, [1R-(1α,4aβ,10aα)]-;Abietic acid, dehydro-6-sulfo- (6CI);Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-12-sulfo- (8CI);13-Isopropyl-12-sulfopodocarpa-8,11,13-trien-15-oic acid
• CAS NO: 33159-27-2
• Molecular Formula: C₂₀H₂₈O₅S
• Molecular Weight: 380.502
• Mol File: 33159-27-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.241 g/cm³
• Refractive Index: 1.562
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.31±0.60(Predicted)
• CAS DataBase Reference: Ecabet(CAS DataBase Reference)
• NIST Chemistry Reference: Ecabet(33159-27-2)
• EPA Substance Registry System: Ecabet(33159-27-2)

Safety Data

• Hazardous Substances Data: 33159-27-2(Hazardous Substances Data)

Usage

General Description

Ecabet is a drug that is used to treat gastric ulcers and gastritis. It works by forming a protective barrier on the surface of the stomach, effectively shielding it from the harmful effects of stomach acid and other irritants. This helps to reduce inflammation and promote healing of the stomach lining. Ecabet has also been found to have antioxidant and anti-inflammatory properties, which may contribute to its therapeutic effects. Additionally, it has been shown to enhance the effectiveness of other medications used to treat gastric ulcers and gastritis. Overall, Ecabet is a valuable chemical in the treatment of gastrointestinal disorders, offering a unique mechanism of action and a range of beneficial effects.

InChI:InChI=1/C20H28O5S/c1-12(2)14-10-13-6-7-17-19(3,8-5-9-20(17,4)18(21)22)15(13)11-16(14)26(23,24)25/h10-12,17H,5-9H2,1-4H3,(H,21,22)(H,23,24,25)/t17-,19-,20-/m1/s1

Upstream product

• 1740-19-8 dehydroabietic acid 
• 514-10-3 abietic acid 

Downstream Products

• 86408-71-1 12-sulfodehydroabietic acid disodium salt 
• 1740-19-8 dehydroabietic acid 
• 86408-72-2 ecabet sodium 

Relevant articles and documents

-

-

One method for preparing card time of special sodium

The invention discloses a method for preparing ecabet sodium. The method disclosed by the invention is characterized by comprising the following steps of carrying out sulfonation reaction on dehydroabietic acid (formula III) as a starting material and fuming sulfuric acid to obtain 12-sulfonic dehydroabietic acid (formula II) and enabling the compound shown as the formula II and a sodium-forming agent to form a sodium salt in a solvent system at least containing water to obtain ecabet sodium. By virtue of the method disclosed by the invention, the deficiencies of the prior art are overcome and the method has the advantage of high sulfonation yield and high selectivity in sodium salt forming, simple operation, safety and environment friendliness and is suitable for industrial production.