332163-01-6 Usage
General Description
4,5-DIMETHOXY-2-[(THIOPHENE-2-CARBONYL)-AMINO]-BENZOIC ACID is a chemical compound with potential pharmaceutical applications. It is a derivative of benzoic acid with two methoxy groups and a thiophene-2-carbonyl-amino group attached to the benzene ring. The presence of the thiophene-2-carbonyl-amino group suggests potential interactions with biological systems, making it a candidate for drug development. The compound's specific pharmacological properties and potential therapeutic uses would need to be further studied and characterized in order to fully understand its potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 332163-01-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,1,6 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 332163-01:
(8*3)+(7*3)+(6*2)+(5*1)+(4*6)+(3*3)+(2*0)+(1*1)=96
96 % 10 = 6
So 332163-01-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H13NO5S/c1-19-10-6-8(14(17)18)9(7-11(10)20-2)15-13(16)12-4-3-5-21-12/h3-7H,1-2H3,(H,15,16)(H,17,18)/p-1
332163-01-6Relevant articles and documents
The design and synthesis of novel orally active inhibitors of AP-1 and NF-κB mediated transcriptional activation. SAR of in vitro and in vivo studies
Palanki, Moorthy S. S.,Erdman, Paul E.,Ren, Minghuan,Suto, Mark,Bennett, Brydon L.,Manning, Anthony,Ransone, Lynn,Spooner, Cheryl,Desai, Sonal,Ow, Arnie,Totsuka, Ryuichi,Tsao, Peter,Toriumi, Wataru
, p. 4077 - 4080 (2007/10/03)
We have developed novel orally active quinazoline analogues as inhibitors of AP-1 and NF-κB mediated transcriptional activation. Among the derivatives prepared, 1-[2-(2-thienyl)quinazolin-4-ylamino]-3-methyl-3- pyrroline-2,5-dione (10) showed significant activity in an adjuvant-induced arthritis rat model by reducing the swelling by 65% in the non-injected foot. The synthesis, structure-activity relationship, and in vivo activity are described.
