3331-46-2 Usage
Description
9,10-DIHYDROBENZO[A]PYREN-7(8H)-ONE is a ketone polycyclic aromatic hydrocarbon (PAH) that exhibits binding affinity to the zebrafish sex hormone binding globulin (zfSHBG) in the micromolar range. This property suggests potential health risks to humans and other vertebrates due to its interaction with hormone binding proteins.
Uses
Used in Chemical Synthesis:
9,10-DIHYDROBENZO[A]PYREN-7(8H)-ONE serves as a precursor to benzo[a]pyrene derivatives, which are important compounds in various chemical and pharmaceutical applications. Its role as a precursor allows for the synthesis of a range of benzo[a]pyrene-related compounds with diverse properties and uses.
Used in Environmental and Health Research:
As a ketone PAH that binds to zfSHBG, 9,10-DIHYDROBENZO[A]PYREN-7(8H)-ONE is utilized in research aimed at understanding the impact of environmental pollutants on hormone regulation and overall health in humans and other vertebrates. This research is crucial for developing strategies to mitigate the risks associated with exposure to such compounds.
Used in Pharmaceutical Development:
Given its binding properties, 9,10-DIHYDROBENZO[A]PYREN-7(8H)-ONE may also be used in the development of pharmaceuticals targeting hormone-related conditions. Its interaction with hormone binding proteins could potentially be leveraged to create drugs that modulate hormone levels or disrupt the activity of harmful environmental pollutants.
Check Digit Verification of cas no
The CAS Registry Mumber 3331-46-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,3 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3331-46:
(6*3)+(5*3)+(4*3)+(3*1)+(2*4)+(1*6)=62
62 % 10 = 2
So 3331-46-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H14O/c21-18-6-2-5-15-16-10-9-13-4-1-3-12-7-8-14(11-17(15)18)20(16)19(12)13/h1,3-4,7-11H,2,5-6H2
3331-46-2Relevant articles and documents
Dehydrogenation of Nitrogen Heterocycles Using Graphene Oxide as a Versatile Metal-Free Catalyst under Air
Zhang, Jingyu,Chen, Shiya,Chen, Fangfang,Xu, Wensheng,Deng, Guo-Jun,Gong, Hang
supporting information, p. 2358 - 2363 (2017/07/22)
Graphene oxide (GO) has been developed as an inexpensive, environmental friendly, metal-free carbocatalyst for the dehydrogenation of nitrogen heterocycles. Valuable compounds, such as quinoline, 3,4-dihydroisoquinoline, quinazoline, and indole derivatives, have been successfully used as substrates. The investigation of various oxygen-containing molecules with different conjugated systems indicated that both the oxygen-containing groups and large π-conjugated system in GO sheets are essential for this reaction. (Figure presented.).
Carbon-13 labeled benzo[a]pyrenes and derivatives. 4. Labeling the 7-10 positions
Klassen,Daub,Vanderjagt
, p. 4361 - 4366 (2007/10/02)
-
