333743-54-7

Basic information

• Product Name: Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI);(R)-tert-butyl 2-aminopropylcarbamate;R-1-N-BOC-propane-1,2-diamine-HCl;tert-butyl N-[(2R)-2-aMinopropyl]carbaMate;(R)-1-N-Boc-Propane-1,2-diaMine hydrochloride;R-1-n-boc-propane-1,2-diaMine;((R)-2-Aminopropyl)carbamic acid tert-butyl ester;[(R)-2-Amino-1-propyl]carbamic acid tert-butyl ester
• CAS NO: 333743-54-7
• Molecular Formula: C₈H₁₈N₂O₂
• Molecular Weight: 174.24072
• Product Categories: N-BOC
• Mol File: 333743-54-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 264℃
• Flash Point: 113℃
• Appearance: /
• Density: 0.984
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 12.51±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI)(333743-54-7)
• EPA Substance Registry System: Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI)(333743-54-7)

Safety Data

• Hazardous Substances Data: 333743-54-7(Hazardous Substances Data)

Usage

General Description

Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI) is a chemical compound with the molecular formula C7H16N2O2. It is the tertiary butyl ester of (R)-2-aminopropanol carbamic acid and is used in the production of various pharmaceuticals and agricultural chemicals. Carbamic acid, [(2R)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI) is known for its ability to inhibit certain enzymes and has potential applications in the treatment of neurological disorders and as a pesticide. It is important to handle this chemical with care and follow proper safety protocols due to its potential toxicity and health hazards.

Upstream product

• 333743-53-6 (2R)-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-propyl]carbamic acid 1,1-dimethylethylester 
• 6627-89-0 tert-butyl phenyl carbonate 
• 19777-66-3 (R)-propane-1,2-diamine dihydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 333743-55-8 [(2R)-2-[[2-amino-5-[(phenylmethyl)thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]propyl]carbamic acid 1,1-dimethylethyl ester 
• 400652-52-0 (R)-2-(benzyloxycarbonylaminopropyl)carbamic acid tert-butyl ester 
• 1206600-49-8 3-[benzyloxycarbonyl-((R)-2-tert-butoxycarbonylamino-1-methyl-ethyl)-amino]-propionic acid methyl ester 
• 333743-56-9 [(2R)-2-[[2-amino-5-[(phenylmethyl)sulfonyl]thiazolo[4,5-d]pyrimidin-7-yl]amino]propyl]carbamic acid 1,1-dimethylethyl ester 
• 333743-57-0 [(2R)-2-[[2-amino-5-[[(3-chloro-2-fluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]propyl]carbamic acid 1,1-dimethylethyl ester 

Relevant articles and documents

Synthesis and properties of chiral internally branched PAMAM-dendrimers

Improved synthetic methodology for the synthesis of internally branched chiral poly(amidoamine) (PAMAM) dendrons and dendrimers has been developed and the compounds have been characterized by NMR spectroscopy, IR spectroscopy, and optical rotation measurements. The dendrons and dendrimers show increased degree of internal hydrogen bonding upon increasing generation and the presence of different types of amide-protons in the compounds is indicative of the existence of a tertiary structure in these PAMAM-dendrimers.

AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain amino-ethyl-amino-aryl (AEAA) compounds which, inter alia, inhibit protein kinase D (PKD) (e.g., PKD1, PKD2, PKD3). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit PKD, and in the treatment of diseases and conditions that are mediated by PKD, that are ameliorated by the inhibition of PKD, etc., including proliferative conditions such as cancer, etc.