333998-14-4Relevant articles and documents
A 2′-acylamido cap that increases the stability of oligonucleotide duplexes
Kryatova, Olga P.,Connors, William H.,Bleczinski, Colleen F.,Mokhir, Andriy A.,Richert, Clemens
, p. 987 - 990 (2007/10/03)
(matrix presented) Reported here is the synthesis of oligonucleotides containing a 2′-acylamido-2′-deoxyuridine residue at their 3′-terminus. Compared to control sequences bearing a thymidine residue, the quinolone-capped duplexes give higher UV melting p