33417-27-5 Usage
Main Properties
1. Chemical Formula: C13H11NO
2. Functional Groups:
Primary amine group ( -NH2 )
Hydroxyl group ( -OH )
3. Derivation: Derived from fluorene
4. Fluorescent Properties: Exhibits fluorescence
5. Applications:
Organic Chemistry Reagent: Used in the synthesis of various organic compounds
Fluorescent Probe: Utilized in biological and environmental research
Pharmaceutical and Material Development: Potential applications in pharmaceuticals and materials due to its unique structure and properties
Specific Content
1. Chemical Name: 2-Amino-9-fluorenol
2. Alternative Name: 9-Hydroxyfluorene-2-amine
3. Composition: Contains 13 carbon atoms, 11 hydrogen atoms, 1 nitrogen atom, and 1 oxygen atom
4. Functional Group Positioning: Primary amine group is located at position 2 and the hydroxyl group is located at position 9 on the fluorene ring.
5. Utility in Organic Synthesis: Facilitates the creation of diverse organic compounds through chemical reactions.
6. Fluorescence Application: Used to label biomolecules or environmental components for visualization under fluorescence microscopy.
7. Potential in Pharmaceutical Development: Being explored for its pharmacological properties and potential in drug discovery.
8. Material Science Exploration: Investigated for its suitability in designing novel materials with specific properties.
This compound, with its dual functional groups and fluorescent nature, holds promise in various fields of science, from organic chemistry to materials science and biomedical research.
Check Digit Verification of cas no
The CAS Registry Mumber 33417-27-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,4,1 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 33417-27:
(7*3)+(6*3)+(5*4)+(4*1)+(3*7)+(2*2)+(1*7)=95
95 % 10 = 5
So 33417-27-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H11NO/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)12(10)7-8/h1-7,13,15H,14H2
33417-27-5Relevant articles and documents
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Morgan,Stewart
, p. 1454,1456 (1933)
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Reductions of nitro and 9-oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro
Ritter,Decker,Malejka-Giganti
, p. 793 - 800 (2007/10/03)
Nitrofluorenes and C-9-oxidized nitrofluorenes are widespread environmental genotoxins which may be relevant for breast cancer on the basis of their carcinogenicities, particularly of 2,7-dinitrofluorene (2,7-diNF), for the rat mammary gland. Since their metabolism to active carcinogens may involve nitroreduction, this study examined the reduction of 2-nitrofluorene (2-NF) and 2,7-diNF and their 9-oxo- and 9-hydroxy (OH) derivatives by the rat mammary gland. Cytosolic fractions catalyze NADH- and NADPH-dependent reductions of the 2-nitro and 9-oxo to the respective 2-amino and 9-OH compounds at rates 4- and ≥10-fold greater than those with microsomes. Rates of amine formation catalyzed by cytosol from 2,7-diNF are greater than the rate from 2-NF and increase for C-9-oxidized derivatives: 9-oxo-2-NF >> 9-OH-2-NF > 2-NF and 9-OH-2,7-diNF 9-oxo-2,7-diNF >> 2,7-diNF. Nitroreduction is inhibited by O2 or allopurinol (20 μM), dicoumarol (100 μM), and rutin (50 μM). 9-Oxoreduction is inhibited by rutin, dicoumarol, and indomethacin (100 μM), but not by O2 or allopurinol. Pyrazole or menadione does not inhibit nitro or 9-oxoreduction. Xanthine, hypoxanthine, 2-hydroxypyrimidine, and N'-methylnicotinamide support cytosol-catalyzed nitro, but not 9-oxo, reduction. The data suggest that the nitroreduction is catalyzed largely by a xanthine oxidase and partially by a diaphorase and 9-oxoreduction by a carbonyl reductase. The extents of the nitro and carbonyl reductions of the nitrofluorenes may determine their reactivities with DNA, and thus genotoxicities for the mammary gland.
Route to the tritiation of carbon atom 9 of carcinogenic fluorenylhydroxamic acids
Gutmann,Bell
, p. 255 - 270 (2007/10/06)
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