3347-03-3

Basic information

• Product Name: Benzenesulfonothioic acid, 4-bromo-, S-(4-bromophenyl) ester
• Synonyms: S-4-bromophenyl 4-bromobenzenesulfonothioate;4.4'-Dibrom-diphenyldisulfoxyd;S-4-bromophenyl 4-bromobenzenethiosulfonate
• CAS NO: 3347-03-3
• Molecular Formula: C12H8Br2O2S2
• Molecular Weight: 408.134
• Mol File: 3347-03-3.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzenesulfonothioic acid, 4-bromo-, S-(4-bromophenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonothioic acid, 4-bromo-, S-(4-bromophenyl) ester(3347-03-3)
• EPA Substance Registry System: Benzenesulfonothioic acid, 4-bromo-, S-(4-bromophenyl) ester(3347-03-3)

Safety Data

• Hazardous Substances Data: 3347-03-3(Hazardous Substances Data)

Upstream product

• 75168-73-9 4-bromobenzenesulfonyl chloride 
• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 2297-64-5 p-bromophenylsulfonyl hydrazide 
• 96-09-3 styrene oxide 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 1950-68-1 4-methoxybenzenesulfonyl hydrazide 
• 106-53-6 para-bromobenzenethiol 
• 34176-08-4 sodium 4-bromobenzenesulfinate 
• 25752-90-3 tert-butyl 4-bromophenyl sulfide 
• 117292-62-3 4-bromophenyl tert-butyl sulfoxide 
• 1762-76-1 4-bromobenzenesulfenyl chloride 
• 5335-84-2 bis(4-bromophenyl)disulfide 
• 1195-33-1 4-bromo-benzenesulfinic acid 

Downstream Products

• 333-47-1 1-bromo-4-(trifluoromethyl)thiobenzene 

Relevant articles and documents

Nickel-Catalyzed Difunctionalization of Alkynyl Bromides with Thiosulfonates and N -Arylthio Succinimides: A Convenient Synthesis of 1,2-Thiosulfonylethenes and 1,1-Dithioethenes

An efficient nickel-catalyzed vicinal thiosulfonylation of 1-bromoalkynes with thiosulfonates in the presence of cesium carbonate is described. An operationally simple and highly regioselective atom transfer radical addition (ATRA) of alkynyl bromides provides a wide range of (E)-1,2-thiosulfonylethenes (α-aryl-β-thioarylvinyl sulfones) in moderate to high yields. The extensive substrate scope of both alkynyl bromides and thiosulfonates is explored with a broad range of functional groups. Indole-derived 1,1-bromoalkenes were also successfully explored in this 1,2-thiosulfonylation process. Moreover, the nickel-catalyzed geminal -dithiolation of alkynyl bromides with N -arylthio succinimides provides 1,1-dithioalkenes in high yields. The present protocol is reliable on gram scale, and a sequential one-pot bromination and thiosulfonylation of phenylacetylene is achieved in a scale-up synthesis. Following control experiments, a plausible mechanism is proposed to rationalize the experimental outcome and the vicinal thio-sulfonylation.

The organocatalytic synthesis of perfluorophenylsulfides: Via the thiolation of trimethyl(perfluorophenyl)silanes and thiosulfonates

The organic superbase t-Bu-P4-catalyzed direct thiolation of trimethyl(perfluorophenyl)silanes and thiosulfonates was developed. Yields of perfluorophenylsulfides of up to 97% under catalysis of 5 mol% t-Bu-P4 were achieved. This method was shown to provide an efficient way to construct the perfluorophenyl-sulfur bond under mild metal-free reaction conditions. This journal is

H4SiW12O40-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides: An efficient synthesis of 3,4-disubstituted 1H-pyrazoles

A simple and efficient method for the synthesis of pyrazoles through a silicotungstic acid (H4SiW12O40)-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides has been developed. Various epoxides/aldehydes were smoothly reacted with sulfonyl hydrazides to furnish regioselectivity 3,4-disubstituted 1H-pyrazoles. The application of such an earth-abundant, readily accessible, and nontoxic catalyst provides a green approach for the construction of 3,4-disubstituted 1H-pyrazoles. A plausible reaction mechanism has been proposed on the basis of control experiments, GC-MS and DFT calculations.