33543-78-1 Usage
Description
ETHYL IMIDAZOLE-2-CARBOXYLATE is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its light brown powder form and plays a significant role in the development of drugs targeting specific enzymes and receptors in the medical field.
Uses
Used in Pharmaceutical Industry:
ETHYL IMIDAZOLE-2-CARBOXYLATE is used as an intermediate for the synthesis of tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1). These inhibitors are essential in the development of therapeutic agents for the treatment of various diseases, including cancer.
Used in Anticonvulsant Applications:
ETHYL IMIDAZOLE-2-CARBOXYLATE is also used to prepare imidazoindenopyrazinone carboxylic acid derivatives, which exhibit AMPA antagonist properties with anticonvulsant activities. These derivatives have potential applications in the treatment of epilepsy and other seizure disorders, providing an alternative approach to managing these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 33543-78-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,5,4 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 33543-78:
(7*3)+(6*3)+(5*5)+(4*4)+(3*3)+(2*7)+(1*8)=111
111 % 10 = 1
So 33543-78-1 is a valid CAS Registry Number.
33543-78-1Relevant articles and documents
Orthogonally positioned diamino pyrrole- and imidazole-containing polyamides: Synthesis of 1-(3-substituted-propyl)-4-nitropyrrole-2-carboxylic acid and 1-(3-Chloropropyl)-4-nitroimidazole-2-carboxylic Acid
Satam, Vijay,Patil, Pravin,Babu, Balaji,Rice, Toni,Porte, Alexander,Alger, Shannon,Zeller, Matthias,Lee, Moses
, p. 968 - 975 (2014)
Pyrrole- and imidazole-containing polyamides can be tailored to recognize the DNA 6-8 base pair sequence. We found that adding a second amino group via the N1-position of pyrrole or imidazole in polyamides could enhance their DNA binding affinity and wate
CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION
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Page/Page column 108-109, (2011/12/04)
Chemical compounds that modulate kinase activity, including PI3 kinase activity, and chemical compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND
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Page/Page column 32-33, (2010/02/14)
The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
