33631-02-6

Basic information

• Product Name: 3,4-Diamino-2-hydroxypyridine
• Synonyms: 3,4-Diamino-2-hydroxypyridine;3,4-Diamino-2-pyridinol;2(1H)-Pyridinone,3,4-diamino-(9CI);3,4-DIAMINOPYRIDIN-2-OL;3,4-Diamino-1H-pyridin-2-one;4-diaMino-;2(1H)-Pyridinone,3,4-diamino-
• CAS NO: 33631-02-6
• Molecular Formula: C₅H₇N₃O
• Molecular Weight: 125.12858
• Product Categories: PYRIDINE
• Mol File: 33631-02-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 545.7°Cat760mmHg
• Flash Point: 283.8°C
• Appearance: /
• Density: 1.46g/cm³
• Vapor Pressure: 0.000471mmHg at 25°C
• Refractive Index: 1.493
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 3,4-Diamino-2-hydroxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Diamino-2-hydroxypyridine(33631-02-6)
• EPA Substance Registry System: 3,4-Diamino-2-hydroxypyridine(33631-02-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 33631-02-6(Hazardous Substances Data)

Usage

General Description

3,4-Diamino-2-hydroxypyridine, also known as 2-Amino-3,4-dihydroxypyridine, is a chemical compound commonly used in the pharmaceutical and cosmetics industries. It is a pyridine derivative with two amino groups and a hydroxy group attached to the aromatic ring. 3,4-Diamino-2-hydroxypyridine has demonstrated antioxidant and anti-inflammatory properties, making it a potential candidate for the treatment of various diseases and conditions. It is also commonly used in hair dyes and colorants, where it acts as a coloring agent. 3,4-Diamino-2-hydroxypyridine is a versatile chemical with a range of potential applications in multiple industries.

InChI:InChI=1/C7H6F3NO2S/c8-7(9,10)5-2-1-3-6(4-5)14(11,12)13/h1-4H,(H2,11,12,13)

Upstream product

• 1681-37-4 4-amino-3-nitropyridine 
• 3243-24-1 imidazo<4,5-c>pyridine-4-one 
• 88511-57-3 4-amino-3-nitro-pyridin-2-ol 

Downstream Products

• 272-97-9 Imidazo<4,5-c>pyridin 
• 679797-41-2 pyrido[3,4-b]pyrazin-5(6H)-one 

Relevant articles and documents

3,4-DISUBSTITUTED PYRAZOLES AS CYCLIN DEPENDENT KINASES (CDK) OR AURORA KINASE OR GLYCOGEN SYNTHASE 3 (GSK-3) INHIBITORS

The invention provides compounds of the formula (I); or salts or solvates or N-oxides thereof; wherein: Rq is selected from groups (a), (b) and (c); the asterisk denoting the point of attachment to the pyrazole ring; X is N or CR5; X" is NR4', O, S or S(O); A is a bond or -(CH2)m-(B)n-; B is C=O, NRg(C=O) or O(C=O) wherein Rg is hydrogen or C1-4 hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy; m is 0, 1 or 2; n is 0 or 1; R0 is hydrogen or, together with NRg when present, forms a group -(CH2)p- wherein p is 2 to 4; and R1 to R6b are as defined in the description. Compounds of the formula (I) have activity as inhibitors of CDK, aurora and GSK-3 kinases are useful in treating or preventing diseases such as cancers that are mediated by the said kinases.