33657-49-7 Usage
Description
CHLOROMETHYL BUTYRATE is an organic compound that is colorless to almost colorless in appearance. It is a versatile chemical intermediate used in the synthesis of various pharmaceuticals and other chemical products.
Uses
Used in Pharmaceutical Industry:
CHLOROMETHYL BUTYRATE is used as a synthetic intermediate for the production of clevidipine, a short-acting antihypertensive drug. Clevidipine incorporates a methoxymethyl ester, which is readily cleaved to the corresponding acid by serum esterases. The preparation of this compound is achieved through simple alkylation of the monoester with CHLOROMETHYL BUTYRATE.
Used in Chemical Synthesis:
CHLOROMETHYL BUTYRATE serves as a valuable building block in the synthesis of various chemical products. Its reactivity and functional groups make it a useful compound in the development of new materials and chemicals for different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 33657-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,6,5 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 33657-49:
(7*3)+(6*3)+(5*6)+(4*5)+(3*7)+(2*4)+(1*9)=127
127 % 10 = 7
So 33657-49-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H9ClO2/c1-2-3-5(7)8-4-6/h2-4H2,1H3
33657-49-7Relevant articles and documents
Chlorination of Esters. I. Chlorination of Methyl Esters of Propanoic, Butanoic, Pentanoic and Hexanoic Acids. The Isomer Distribution of Monochloro Esters Formed
Korhonen, Ilpo O.O.,Korvola, Jorma N.J.
, p. 139 - 142 (2007/10/02)
The chlorination of methyl ester with chlorine in the liquid and vapor phase and with sulfuryl chloride in the liquid phase has been investigated.The chlorination yields all possible monochloro esters isomers with the 2-chloro isomer in the smallest amount.The products were identified by NMR and mass spectrometry.The isomer distribution and mass spectra of products were studied in detail.
