33757-51-6Relevant articles and documents
Aryne Multicomponent Reactions by Directed C?H Activation
Sunnam, Sunil Kumar,Belani, Jitendra D.
, p. 8846 - 8850 (2021)
Arylation via ortho C?H activation by the aid of directing groups has been explored recently by many researchers. Herein, a palladium-catalyzed C?H arylation using 8-aminoquinoline as a bidentate directing group has been developed. The reaction furnishes only C?H arylation, unlike previous methods where cyclization to corresponding isoquinolones is observed. More interestingly, sequential C?H functionalization was observed when methylacrylate and acrylonitrile was added; this led to C?H olefination with the aryl group, which was installed from the aryne precursor.
Rhodium-Catalyzed Alkenylation of C-H Bonds in Aromatic Amides with Alkynes
Shibata, Kaname,Natsui, Satoko,Chatani, Naoto
supporting information, p. 2234 - 2237 (2017/05/12)
The rhodium-catalyzed alkenylation of C-H bonds of aromatic amides with alkynes is reported. A variety of functional groups, including OMe, OAc, Br, Cl, and even NO2, are applicable to this reaction to give the corresponding hydroarylation prod
Copper(ii)-catalyzed C5 and C7 halogenation of quinolines using sodium halides under mild conditions
Xu, Jun,Zhu, Xiaolei,Zhou, Guobin,Ying, Beibei,Ye, Pingping,Su, Lingying,Shen, Chao,Zhang, Pengfei
, p. 3016 - 3021 (2016/03/19)
A simple and mild protocol for copper catalyzed halogenation of quinoline at C5 and C7 positions was developed, affording the desired remote C-H activation products in moderate to good yields. This reaction proceeds with low-cost sodium halides (NaX, X =
