33769-07-2Relevant articles and documents
Targeting GRP receptor: Design, synthesis and preliminary biological characterization of new non-peptide antagonists of bombesin
Palmioli, Alessandro,Nicolini, Gabriella,Tripodi, Farida,Orsato, Alexandre,Ceresa, Cecilia,Donzelli, Elisabetta,Arici, Martina,Coccetti, Paola,Rocchetti, Marcella,La Ferla, Barbara,Airoldi, Cristina
supporting information, (2021/02/27)
We report the rational design, synthesis, and in vitro preliminary evaluation of a new small library of non-peptide ligands of Gastrin Releasing Peptide Receptor (GRP-R), able to antagonize its natural ligand bombesin (BN) in the nanomolar range of concen
HETEROARYL RHEB INHIBITORS AND USES THEREOF
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Paragraph 00401, (2018/11/10)
The present invention provides compounds, compositions thereof, and methods of using the same. Compositions comprising a compound of this invention or a pharmaceutically acceptable derivative thereof and a pharmaceutically acceptable carrier, adjuvant, or vehicle. The amount of the compound in compositions of this invention is such that it is effective to measurably inhibit Rheb, in a biological sample or in a patient.
Synthesis method of calmodulin inhibitor for treating brain-derived diseases
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Paragraph 0033; 0034; 0035, (2017/08/29)
The invention discloses a synthesis method of a calmodulin inhibitor for treating brain-derived diseases and belongs to the technical field of synthesis of chemicals. The technical scheme is characterized in that a synthetic route of the synthesis method