339-83-3

Basic information

• Product Name: (11beta)-21-fluoro-11-hydroxypregn-4-ene-3,20-dione
• Synonyms: 21-Fluoro-11beta-hydroxypregn-4-ene-3,20-dione; 21-Fluoro-11beta-hydroxyprogesterone
• CAS NO: 339-83-3
• Molecular Formula: C₂₁H₂₉FO₃
• Molecular Weight: 348.4516
• Mol File: 339-83-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 501.2°C at 760 mmHg
• Flash Point: 256.9°C
• Density: 1.19g/cm³
• Vapor Pressure: 3.8E-12mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: (11beta)-21-fluoro-11-hydroxypregn-4-ene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (11beta)-21-fluoro-11-hydroxypregn-4-ene-3,20-dione(339-83-3)
• EPA Substance Registry System: (11beta)-21-fluoro-11-hydroxypregn-4-ene-3,20-dione(339-83-3)

Safety Data

• Hazardous Substances Data: 339-83-3(Hazardous Substances Data)

Usage

Description

(11beta)-21-fluoro-11-hydroxypregn-4-ene-3,20-dione, commonly known as dexamethasone, is a synthetic corticosteroid medication that exhibits potent anti-inflammatory and immunosuppressive properties. It is structurally derived from the natural hormone cortisol, with modifications that enhance its therapeutic efficacy and reduce systemic side effects. Dexamethasone is widely used in medical treatments due to its ability to alleviate inflammation and suppress the immune system.
Used in Pharmaceutical Industry:
Dexamethasone is used as an anti-inflammatory and immunosuppressive agent for treating a variety of conditions, such as inflammatory disorders, allergic reactions, and certain types of cancer. Its application reason lies in its ability to reduce inflammation and suppress the immune system, providing relief from severe symptoms and managing the progression of diseases.
Used in Respiratory Conditions:
In the treatment of respiratory conditions like asthma, dexamethasone is used as a medication to reduce inflammation in the airways, improving breathing and managing acute exacerbations.
Used in Autoimmune and Rheumatic Diseases:
Dexamethasone is utilized as a treatment for autoimmune and rheumatic diseases, such as rheumatoid arthritis, due to its capacity to alleviate inflammation and mitigate pain associated with these conditions.
Used in Dermatological Applications:
For certain skin disorders, dexamethasone is employed as a topical treatment to reduce inflammation, itching, and redness, promoting healing and improving the appearance of the skin.
Used in Ophthalmic Applications:
In the form of eye drops, dexamethasone is used as an anti-inflammatory agent to treat eye conditions such as uveitis, reducing inflammation and discomfort.