3395-83-3

Basic information

• Product Name: p-(dimethoxymethyl)toluene
• Synonyms: p-(dimethoxymethyl)toluene;p-(Dimethoxymethyl)toluol;1-(Dimethoxymethyl)-4-methylbenzene;1-Dimethoxymethyl-4-methylbenzene;p-Methylbenzaldehyde dimethyl acetal;p-Tolualdehyde dimethyl acetal;Benzene, 1-(dimethoxymethyl)-4-methyl-;Einecs 222-244-9
• CAS NO: 3395-83-3
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• EINECS: 222-244-9
• Mol File: 3395-83-3.mol
• Article Data: 68

Chemical Properties

• Boiling Point: 196.2°Cat760mmHg
• Flash Point: 58.4°C
• Appearance: /
• Density: 0.986g/cm³
• Vapor Pressure: 0.567mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: p-(dimethoxymethyl)toluene(CAS DataBase Reference)
• NIST Chemistry Reference: p-(dimethoxymethyl)toluene(3395-83-3)
• EPA Substance Registry System: p-(dimethoxymethyl)toluene(3395-83-3)

Safety Data

• Hazardous Substances Data: 3395-83-3(Hazardous Substances Data)

Usage

General Description

p-(dimethoxymethyl)toluene is a chemical compound with the molecular formula C9H12O2. It is a derivative of toluene, with the methoxy group attached to the para position of the benzene ring and the methoxymethyl group attached to the methyl group of toluene. p-(dimethoxymethyl)toluene is often used in the production of fragrances and flavorings due to its aromatic properties. It can also be utilized as a solvent and an intermediate in the synthesis of other organic compounds. Additionally, p-(dimethoxymethyl)toluene has potential applications in the pharmaceutical and cosmetic industries. However, it is important to handle this chemical with care as it may have health and environmental hazards if not properly managed.

InChI:InChI=1/C10H14O2/c1-8-4-6-9(7-5-8)10(11-2)12-3/h4-7,10H,1-3H3

Upstream product

• 616-42-2 dimethylsulfite 
• 104-87-0 4-methyl-benzaldehyde 
• 67-56-1 methanol 
• 106-42-3 para-xylene 
• 2698-14-8 1-methyl-4-(prop-1-enyl)benzene 
• 149-73-5 trimethyl orthoformate 
• 7450-04-6 1-((trimethylsilyl)methyl)-4-methylbenzene 
• 35779-32-9 1,3,5-tris(4-methylphenyl)-2,4-diazapenta-1,4-diene 
• 124-41-4 sodium methylate 
• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 74-88-4 methyl iodide 
• 622-97-9 1-ethenyl-4-methylbenzene 

Downstream Products

• 56377-70-9 (α-chloro-4-methyl-benzyl)-methyl ether 
• 63523-40-0 N-(methoxy-p-tolyl-methyl)-4-methyl-thiobenzamide 
• 22911-22-4 1-methyl-4-(trimethoxymethyl)benzene 
• 93943-06-7 4-(methoxymethyl)benzaldehyde 
• 623-27-8 terephthalaldehyde, 
• 1571-08-0 methyl 4-formylbenzoate 
• 124828-71-3 1-methoxy-1-(p-tolyl)hept-2-yne 
• 114533-85-6 1-Methyl-4-(1,3,3-trimethoxy-propyl)-benzene 
• 87505-91-7 2-<(4-methylphenyl)methoxymethyl>-2-(trimethylsiloxy)cyclobutanone 
• 128720-16-1 α-methoxy-4-methylphenylacetonitrile 
• 106732-38-1 1-((R)-1-Methoxy-2-methyl-but-3-enyl)-4-methyl-benzene 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 104-87-0 4-methyl-benzaldehyde 
• 911798-06-6 meso-1,2-bis-(4-dimethylphenyl)-1,2-dimethoxyethane 

Relevant articles and documents

Electrochemical Obtention of cis- and trans-3,6-Dimethoxy-3,6-dimethyl-1,4-cyclohexadienes

-

Thiol-initiated photocatalytic oxidative cleavage of the C=C bond in olefins and its extension to direct production of acetals from olefins

The oxidative cleavage of olefins to produce aldehydes/ketones is an important reaction in organic syntheses. In this manuscript, a mild and operationally simple protocol for the aerobic oxidation of olefins to produce carbonyl compounds was realized over ZnIn2S4under visible light, using air as the oxidant and a thiol as the initiator. It was proposed that the photogenerated holes over ZnIn2S4attack the thiol to produce thiyl radicals, which initiate the oxidative cleavage of the C=C bond in olefins to produce aldehydes/ketones. By further coupling with the condensation between the as-obtained aldehydes/ketones and alcohols, this strategy can also be applied to the production of different acetals directly from the olefins. This study demonstrates a new pathway to realize the oxidative cleavage of olefins to produce aldehydes/ketones, and also provides a new protocol for the production of acetals directly from the olefins.

MOF-808 as a recyclable catalyst for the photothermal acetalization of aromatic aldehydes

Metal-organic frameworks (MOFs) show promise for catalysis applications due to their porosity, high internal surface area, and structural adaptability. Typical acetylation reactions of aldehydes require elevated temperatures and excess alcohol to drive the reactions to completion. In this current work, MOF-808 is used as a heterogeneous catalyst for acetylation of aldehydes in methanol using a mild photothermal process. Optimized conditions gave 72% yield of 2-(dimethoxymethyl)naphthalene in the presence of 10 mol% MOF-808 at 45 °C using only a fluorescent lamp. MOF-808 can be recycled up to 5 times with no loss in catalytic activity. A proof-of-principle substrate scope demonstrates the potential utility for aromatic and aliphatic substrates.