34059-10-4Relevant articles and documents
Hydrosilylative reduction of primary amides to primary amines catalyzed by a terminal [Ni-OH] complex
Bera, Jitendra K.,Pandey, Pragati
supporting information, p. 9204 - 9207 (2021/09/20)
A terminal [Ni-OH] complex1, supported by triflamide-functionalized NHC ligands, catalyzes the hydrosilylative reduction of a range of primary amides into primary amines in good to excellent yields under base-free conditions with key functional group tolerance. Catalyst1is also effective for the reduction of a variety of tertiary and secondary amides. In contrast to literature reports, the reactivity of1towards amide reduction follows an inverse trend,i.e., 1° amide > 3° amide > 2° amide. The reaction does not follow a usual dehydration pathway.
Direct Intermolecular Anti-Markovnikov Hydroazidation of Unactivated Olefins
Li, Hongze,Shen, Shou-Jie,Zhu, Cheng-Liang,Xu, Hao
supporting information, p. 9415 - 9421 (2019/06/21)
We herein report a direct intermolecular anti-Markovnikov hydroazidation method for unactivated olefins, which is promoted by a catalytic amount of bench-stable benziodoxole at ambient temperature. This method facilitates previously difficult, direct addition of hydrazoic acid across a wide variety of unactivated olefins in both complex molecules and unfunctionalized commodity chemicals. It conveniently fills a synthetic chemistry gap of existing olefin hydroazidation procedures, and thereby provides a valuable tool for azido-group labeling in organic synthesis and chemical biology studies.
Bis-arylalkenylalkyl acid compound, and preparation method and application thereof
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Paragraph 0114; 0115; 0116; 0117; 0118; 0119; 0120; 0121, (2016/10/07)
The invention relates to a bis-arylalkenylalkyl acid compound, and a preparation method and an application thereof. The structure of the compound is represented by the formula I. the definitions of *, R1, R2, R3, n1 and m are as in the specifications and the claims. The bis-arylalkenylalkyl acid compound provided by the invention has relatively high inhibition activity against sensitive strains and resistant strains, and can be used for preparing antibacterial drugs.