3411-03-8

Basic information

• Product Name: 3-Chloro-4-methylbenzaldehyde
• Synonyms: 3-CHLORO-4-METHYLBENZALDEHYDE 97;3-CHLORO-4-METHYLBENZALDEHYDE, 97% MIN.;3-Chloro-p-tolualdehyde;3-Chloro-4-methylbenzaldehyde;2-Chloro-4-formyltoluene;2-Chloro-4-formyltoluene, 3-Chloro-p-tolualdehyde;3-Chloro-4-methylbenzaldehyde 97%
• CAS NO: 3411-03-8
• Molecular Formula: C₈H₇ClO
• Molecular Weight: 154.59
• Product Categories: Aldehydes;C8;Carbonyl Compounds
• Mol File: 3411-03-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 27-31 °C(lit.)
• Boiling Point: 231.95 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: White or colorless/Low Melting Solid or Liquid
• Density: 1.195 g/cm³
• Vapor Pressure: 0.061mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-Chloro-4-methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-4-methylbenzaldehyde(3411-03-8)
• EPA Substance Registry System: 3-Chloro-4-methylbenzaldehyde(3411-03-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 3411-03-8(Hazardous Substances Data)

Usage

Chemical Properties

White or off-white powder

InChI:InChI=1/C8H7ClO/c1-6-2-3-7(5-10)4-8(6)9/h2-5H,1H3

Upstream product

• 95-72-7 2-chloro-1,4-dimethyl-benzene 
• 104-87-0 4-methyl-benzaldehyde 
• 39652-32-9 (3-chloro-4-methylphenyl) methanol 
• 201230-82-2 carbon monoxide 
• 95-49-8 2-methylchlorobenzene 
• 21423-81-4 3-chloro-4-methylbenzonitrile 
• 5162-82-3 3-chloro-4-methylbenzoic acid 

Downstream Products

• 5162-82-3 3-chloro-4-methylbenzoic acid 
• 39652-32-9 (3-chloro-4-methylphenyl) methanol 
• 876493-62-8 5-chloro-4-methyl-2-nitrobenzaldehyde 
• 774481-25-3 N-cyclooctyl-3-chloro-4-methyl-benzylamine 
• 92576-65-3 4-Methyl-3-chlor-benzyliden-bis-chloracetamid 
• 177756-44-4 2-Chloro-4-[(Z)-2-(4-methanesulfonyl-phenyl)-vinyl]-1-methyl-benzene 
• 177756-45-5 1-(3-chloro-4-methyl-phenyl)-2-(4-methanesulfonyl-phenyl)-ethane-1,2-dione 
• 34633-67-5 5-chloro-4-methyl-2-nitro-benzoic acid 
• 62547-79-9 3-(3-Chloro-4-methylphenyl)-3-hydroxypropanoic Acid 

Relevant articles and documents

Method for producing halogen-substituted aromatic aldehyde

In the production method of the invention, a halogen-substituted aromatic compound is reacted with carbon monoxide in the presence of hydrogen fluoride and boron trifluoride into a corresponding halogen-substituted aromatic aldehyde. By the use of hydrogen fluoride and boron trifluoride, the para position to halogen atom is selectively formylated to provide the halogen-substituted aromatic aldehyde in high yields in a short reaction time even at temperatures lower than room temperature.

IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF

Imidazole compounds represented by general formula (I): wherein each symbol is as defined in the specification, and salts thereof, and a pharmaceutical composition containing same are provided. These compounds are useful in treating the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle cell inhibitory action and an allergy inhibitory action.

THE OXIDATION OF ALDEHYDES TO ACIDS WITH CALCIUM HYPOCHLORITE

Calcium hypochlorite is an efficient reagent for the oxidation of aldehydes to the corresponding acids.Reactions are carried out at ambient temperature in aqueous acetonitrile-acetic acid solution.Aliphatic aldehydes and aromatic aldehydes with electron withdrawing groups afford good to excellent yields.Nuclear chlorination is the preferred reaction in aromatic aldehydes with electron donating groups.