34114-57-3Relevant articles and documents
Resolution of racemic 2-amino-1-butanol with immobilised penicillin G acylase
Fadnavis,Sharfuddin, Mohd.,Vadivel
, p. 4495 - 4500 (1999)
Racemic 2-amino-1-butanol has been resolved to obtain (S)-2-amino-1- butanol with >99% e.e. via enantioselective hydrolysis of its N-phenylacetyl derivative with penicillin G acylase immobilised on Eupergit C. (C) 1999 Elsevier Science Ltd.
Ammonium nitrate: A biodegradable and efficient catalyst for the direct amidation of esters under solvent-free conditions
Ramesh, Perla,Fadnavis, Nitin W.
supporting information, p. 138 - 140 (2015/02/19)
A simple, metal-free, and environment-friendly procedure is developed for the direct conversion of esters to amides using ammonium nitrate as a catalyst under solvent-free conditions. Aryls, heteroaryls, and aliphatic esters are easily converted to the corresponding amides in excellent isolated yields (85-99%). An enantiopure ester and amine were both shown to react without racemization. The methodology has been successfully applied to preparation of procainamide.