342612-74-2

Basic information

• Product Name: Pyrazine-2-carboxylic acid ((S)-1-{(1S,2S)-1-[(S)-2-cyclohexyl-1-((S)-1-{hydroxy-[(1H-tetrazol-5-ylmethyl)-carbamoyl]-methyl}-propylcarbamoyl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-3-methyl-butyl)-amide
• CAS NO: 342612-74-2
• Molecular Weight: 699.854
• Mol File: 342612-74-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyrazine-2-carboxylic acid ((S)-1-{(1S,2S)-1-[(S)-2-cyclohexyl-1-((S)-1-{hydroxy-[(1H-tetrazol-5-ylmethyl)-carbamoyl]-methyl}-propylcarbamoyl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-3-methyl-butyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine-2-carboxylic acid ((S)-1-{(1S,2S)-1-[(S)-2-cyclohexyl-1-((S)-1-{hydroxy-[(1H-tetrazol-5-ylmethyl)-carbamoyl]-methyl}-propylcarbamoyl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-3-methyl-butyl)-amide(342612-74-2)
• EPA Substance Registry System: Pyrazine-2-carboxylic acid ((S)-1-{(1S,2S)-1-[(S)-2-cyclohexyl-1-((S)-1-{hydroxy-[(1H-tetrazol-5-ylmethyl)-carbamoyl]-methyl}-propylcarbamoyl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-3-methyl-butyl)-amide(342612-74-2)

Safety Data

• Hazardous Substances Data: 342612-74-2(Hazardous Substances Data)

Upstream product

• 31602-63-8 (1H-tetrazol-5-yl)methanamine 
• 342612-73-1 (S)-3-[(S)-3-Cyclohexyl-2-((2S,3S)-3-methyl-2-{(S)-4-methyl-2-[(pyrazine-2-carbonyl)-amino]-pentanoylamino}-pentanoylamino)-propionylamino]-2-hydroxy-pentanoic acid 
• 342612-72-0 (S)-3-[(S)-3-Cyclohexyl-2-((2S,3S)-3-methyl-2-{(S)-4-methyl-2-[(pyrazine-2-carbonyl)-amino]-pentanoylamino}-pentanoylamino)-propionylamino]-2-hydroxy-pentanoic acid methyl ester 

Relevant articles and documents

Investigation of glycine α-ketoamide HCV NS3 protease inhibitors: Effect of carboxylic acid isosteres

The design and synthesis of tetrapeptide-based α-ketoamides containing prime side acid isosteres HCV NS3 protease inhibitors are described. Tetrazole, sulfonic acid, and N-sulfonylcarboxamids were demonstrated to be efficient carboxylic acid replacements.