34297-84-2

Basic information

• Product Name: Oxazolo[4,5-c]pyridine, 2-phenyl-
• Synonyms: Oxazolo[4,5-c]pyridine, 2-phenyl-;2-phenylOxazolo[4,5-c]pyridine
• CAS NO: 34297-84-2
• Molecular Formula: C₁₂H₈N₂O
• Molecular Weight: 196.2
• Mol File: 34297-84-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 320.1°C at 760 mmHg
• Flash Point: 146.9°C
• Appearance: /
• Density: 1.241g/cm³
• Vapor Pressure: 0.000607mmHg at 25°C
• Refractive Index: 1.643
• CAS DataBase Reference: Oxazolo[4,5-c]pyridine, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazolo[4,5-c]pyridine, 2-phenyl-(34297-84-2)
• EPA Substance Registry System: Oxazolo[4,5-c]pyridine, 2-phenyl-(34297-84-2)

Safety Data

• Hazardous Substances Data: 34297-84-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H8N2O/c1-2-4-9(5-3-1)12-14-10-8-13-7-6-11(10)15-12/h1-8H

Upstream product

• 15590-89-3 3-aminopyrid-4-one 
• 93-97-0 benzoic acid anhydride 
• 104621-57-0 N-(4-hydroxypyridin-3-yl)benzamide 
• 6320-39-4 3-aminopyridin-4-ol 
• 65-85-0 benzoic acid 
• 5435-54-1 4-hydroxy-3-nitropyridine 
• 15590-90-6 3-nitro-4(1H)-pyridinone 
• 3454-03-3 nitrate 4-hydroxypyridine 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 34282-21-8 4-ethyl-2-phenyl-oxazolo[4,5-c]pyridine 

Relevant articles and documents

Kinase inhibitor, and preparation and application of kinase inhibitor

The invention provides a compound shown as a formula (I), or a stereoisomer, a tautomer, nitrogen oxide, metabolite, a prodrug, pharmaceutically acceptable salt or solvate of the compound, and application of the compound to preparing drugs or drug compositions for treating Pim kinase-mediated diseases.

New facile and mild synthesis of 2-substituted oxazolopyridines

A new, two-step synthesis of oxazolopyridines is described. The synthesis involving amide formation between o-aminopyridinols and aliphatic or aromatic carboxylic acids followed by condensation with hexachloroethane/ triphenylphosphine takes place at room

Anti-inflammatory oxazole[4,5-b]pyridines

The various isomers of oxazolo- and thiazolopyridines having utility as antiinflammatory, antipyretic and analgesic agents are prepared by condensation of an appropriate amino-hydroxypyridine or amino-mercaptopyridine with a carboxylic acid, halide or anhydride.