34334-04-8Relevant articles and documents
Synthesis of nitriles from amines using nanoscale Co3O4-based catalysts via sustainable aerobic oxidation
Natte, Kishore,Jagadeesh, Rajenahally V.,Sharif, Muhammad,Neumann, Helfried,Beller, Matthias
supporting information, p. 3356 - 3359 (2016/04/09)
The selective oxidation of amines for the benign synthesis of nitriles under mild conditions is described. Key to success for this transformation is the application of reusable cobalt oxide-based nanocatalysts. The resulting nitriles constitute key precursors and central intermediates in organic synthesis.
Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities
Fallah-Tafti, Asal,Foroumadi, Alireza,Tiwari, Rakesh,Shirazi, Amir Nasrolahi,Hangauer, David G.,Bu, Yahao,Akbarzadeh, Tahmineh,Parang, Keykavous,Shafiee, Abbas
experimental part, p. 4853 - 4858 (2011/11/29)
KX2-391 (KX-01/Kinex Pharmaceuticals), N-benzyl-2-(5-(4-(2- morpholinoethoxy)phenyl)pyridin-2-yl)acetamide, is a highly selective Src substrate binding site inhibitor. To understand better the role of pyridine ring and N-benzylsubstitution in KX2-391 and
Chemically-tagged Mitsunobu reagents for use in solution-phase chemical library synthesis
Starkey, Gale W.,Parlow, John J.,Flynn, Daniel L.
, p. 2385 - 2390 (2007/10/03)
A general method for high-throughput product purification of Mitsunobu reactions is described. Tagged phosphine and azodicarboxylate reagents are used to synthesize individual library members in solution-phase. Workup and purification are easily accomplished by post-reaction sequestration of the tagged reagents and reagent byproducts by a complementary functionalized ion exchange resin. The reagents are utilized in a 3 step library synthesis.