343945-22-2

Basic information

• Product Name: C₁₃H₁₈O
• CAS NO: 343945-22-2
• Molecular Weight: 190.285
• Mol File: 343945-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₈O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₈O(343945-22-2)
• EPA Substance Registry System: C₁₃H₁₈O(343945-22-2)

Safety Data

• Hazardous Substances Data: 343945-22-2(Hazardous Substances Data)

Upstream product

• 15424-04-1 2-(allyloxy)ethyl bromide 
• 90878-19-6 phenethylmagnesium chloride 

Relevant articles and documents

Bimetallic oxidative addition involving radical intermediates in nickel-catalyzed alkyl-alkyl Kumada coupling reactions

Many nickel-based catalysts have been reported for cross-coupling reactions of nonactivated alkyl halides. The mechanistic understanding of these reactions is still primitive. Here we report a mechanistic study of alkyl-alkyl Kumada coupling catalyzed by a preformed nickel(II) pincer complex ([(N 2N)Ni-Cl]). The coupling proceeds through a radical process, involving two nickel centers for the oxidative addition of alkyl halide. The catalysis is second-order in Grignard reagent, first-order in catalyst, and zero-order in alkyl halide. A transient species, [(N2N)Ni-alkyl 2](alkyl2-MgCl), is identified as the key intermediate responsible for the activation of alkyl halide, the formation of which is the turnover-determining step of the catalysis.