344559-89-3Relevant articles and documents
Regioselective Lewis Acid-mediated α-sec-Alkylation of Carbonyl Compounds
Reetz, Manfred T.,Walz, Peter,Huebner, Friedhelm,Huettenhain, Stefan H.,Heimbach, Horst,Schwellnus, Konrad
, p. 322 - 335 (2007/10/02)
Carbonyl compounds such as ketones, aldehydes, acyloins, or carboxylic esters can be alkylated at the α-position via the corresponding O-silylated forms using activated alkyl halides or acetates in the presence of Lewis acids.In the case of unsymmetricall